Multimodal Imaging in Bilateral Isolated Choroidal Melanocytosis.

Q3 Medicine
Rouzbeh Abbasgholizadeh, Giovanni Bellisario, Ye He, Ceren Soylu, Mai Alhelaly, Srinivas R Sadda
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引用次数: 0

Abstract

Purpose: To report a rare case of bilateral isolated choroidal melanocytosis and highlight the need for thorough imaging evaluation.

Methods: Multimodal imaging, including ultra-widefield fundus photography, fundus autofluorescence, optical coherence tomography (OCT), and OCT angiography, was utilized to assess the findings.

Results: A 58-year-old hispanic female was referred for evaluation of unusual pigmentation in both eyes. She reported occasional floaters but had no other ocular symptoms. Dilated fundus examination and ultra-widefield color fundus imaging revealed extensive choroidal hyperpigmentation involving 360 degrees of the peripheral retina in both eyes. Fundus autofluorescence imaging demonstrated that the hyperpigmented regions were mildly hypofluorescent relative to the less pigmented central regions. Widefield OCT angiography demonstrated absence of any vascular abnormalities in the retina or inner choroid. Widefield structural OCT revealed normal retinal thickness and structure overlying the hyperpigmented areas. There was no choroidal elevation, but the choroidal stroma in the more peripheral regions of the fundus appeared more hyperreflective compared to the presumed normally pigmented central regions. While no choroidal elevation was noted, there was a mild increase in sub-foveal choroidal thickness. No evidence of scleral or periocular cutaneous pigmentation was observed. The overall findings, considering the patient's ethnicity and skin pigmentation, favored a diagnosis of bilateral idiopathic choroidal melanocytosis.

Conclusion: Bilateral isolated choroidal melanocytosis, can be diagnosed accurately through comprehensive imaging. Vigilant monitoring is essential due to the potential risk of malignant transformation.

双侧孤立脉络膜黑色素细胞增多症的多模态成像。
目的:报告一例罕见的双侧孤立性脉络膜黑素细胞增多症,并强调需要进行彻底的影像学评估。方法:采用多模态成像技术,包括超宽视场眼底摄影、眼底自体荧光、光学相干断层扫描(OCT)和OCT血管造影来评估结果。结果:一名58岁的西班牙裔女性因双眼异常色素沉着而被转诊。她偶尔有飞蚊症,但没有其他眼部症状。眼底扩张检查和超广角彩色眼底成像显示双眼周围视网膜360度广泛的脉络膜色素沉着。眼底自身荧光成像显示色素沉着区相对于色素较少的中心区域轻度低荧光。宽视场OCT血管造影显示视网膜或内脉络膜未见任何血管异常。宽视场结构OCT显示正常视网膜厚度和结构覆盖在色素沉着区。没有脉络膜升高,但与假定的正常色素中心区域相比,眼底外围区域的脉络膜间质表现出更高的反射性。虽然没有发现脉络膜升高,但有轻微的中央凹下脉络膜厚度增加。没有发现巩膜或眼周皮肤色素沉着的证据。考虑到患者的种族和皮肤色素沉着,总体结果倾向于诊断为双侧特发性脉络膜黑色素细胞增多症。结论:双侧孤立性脉络膜黑素细胞增多症可通过综合影像学准确诊断。由于恶性转化的潜在风险,警惕监测是必不可少的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Retinal Cases and Brief Reports
Retinal Cases and Brief Reports Medicine-Ophthalmology
CiteScore
2.10
自引率
0.00%
发文量
342
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