Liliana Valladares-Torres, Flavio Edgar Cerón-Betancourth, Jose Guillermo Betancourt-Villalobos, Angelica Benavidez-Jaramillo, Sergio Andrés Montenegro-Herrera
{"title":"Preservation of Porcine Biomodels for the Study of Comparative Human Anatomy.","authors":"Liliana Valladares-Torres, Flavio Edgar Cerón-Betancourth, Jose Guillermo Betancourt-Villalobos, Angelica Benavidez-Jaramillo, Sergio Andrés Montenegro-Herrera","doi":"10.3791/66646","DOIUrl":null,"url":null,"abstract":"<p><p>The teaching of human anatomy in medical education faces challenges, necessitating effective alternatives for students to practically explore anatomical complexity. Porcine biomodels, with their anatomical similarities to humans, offer a promising solution. This article presents a detailed protocol for preserving porcine biomodels, addressing the need for accessible and efficient methods in comparative anatomy studies. This protocol proposes the use of a modified Chilean solution for biomodel preservation, employing formalinization techniques through repletion and immersion. Subsequently, deformalization is achieved using the modified Chilean solution without formaldehyde, followed by a glycerin softening process. Given the scarcity of literature on preservation techniques and the absence of a standardized procedure or test to evaluate tissue conservation, we suggest assessing tissue quality based on measures of resistance and elasticity. Our findings indicate a qualitatively high level of tissue preservation in our specimens. Furthermore, these biomodels are currently utilized successfully for morphology studies and in teaching human comparative anatomy to medical students.</p>","PeriodicalId":48787,"journal":{"name":"Jove-Journal of Visualized Experiments","volume":" 219","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jove-Journal of Visualized Experiments","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.3791/66646","RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The teaching of human anatomy in medical education faces challenges, necessitating effective alternatives for students to practically explore anatomical complexity. Porcine biomodels, with their anatomical similarities to humans, offer a promising solution. This article presents a detailed protocol for preserving porcine biomodels, addressing the need for accessible and efficient methods in comparative anatomy studies. This protocol proposes the use of a modified Chilean solution for biomodel preservation, employing formalinization techniques through repletion and immersion. Subsequently, deformalization is achieved using the modified Chilean solution without formaldehyde, followed by a glycerin softening process. Given the scarcity of literature on preservation techniques and the absence of a standardized procedure or test to evaluate tissue conservation, we suggest assessing tissue quality based on measures of resistance and elasticity. Our findings indicate a qualitatively high level of tissue preservation in our specimens. Furthermore, these biomodels are currently utilized successfully for morphology studies and in teaching human comparative anatomy to medical students.
期刊介绍:
JoVE, the Journal of Visualized Experiments, is the world''s first peer reviewed scientific video journal. Established in 2006, JoVE is devoted to publishing scientific research in a visual format to help researchers overcome two of the biggest challenges facing the scientific research community today; poor reproducibility and the time and labor intensive nature of learning new experimental techniques.