Jiyeong Kim, Juan Pablo Gonzalez Pacheco, Ashleigh Golden, Elias Aboujaoude, Peter van Roessel, Aayushi Gandhi, Pavithra Mukunda, Tatevik Avanesyan, Haopeng Xue, Ehsan Adeli, Jane Paik Kim, Manish Saggar, Shannon Wiltsey Stirman, Eric Kuhn, Kaustubh Supekar, Kilian M Pohl, Carolyn I Rodriguez
{"title":"Artificial Intelligence in Obsessive-Compulsive Disorder: A Systematic Review.","authors":"Jiyeong Kim, Juan Pablo Gonzalez Pacheco, Ashleigh Golden, Elias Aboujaoude, Peter van Roessel, Aayushi Gandhi, Pavithra Mukunda, Tatevik Avanesyan, Haopeng Xue, Ehsan Adeli, Jane Paik Kim, Manish Saggar, Shannon Wiltsey Stirman, Eric Kuhn, Kaustubh Supekar, Kilian M Pohl, Carolyn I Rodriguez","doi":"10.1007/s40501-025-00359-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>Obsessive-compulsive disorder (OCD) is a chronic and disabling condition, often leading to significant functional impairments. Despite its early onset, there is an average delay of 17 years from symptom onset to diagnosis and treatment, resulting in poorer outcomes. This systematic review aims to synthesize current findings on the application of AI in OCD, highlighting opportunities for early symptom detection, scalable therapy training, clinical decision support, novel therapeutics, computer vision-based approaches, and multimodal biomarker discovery.</p><p><strong>Recent findings: </strong>While previous reviews focused on biomarker-based OCD detection and treatment using machine learning (ML), the findings of the current review add information about novel applications of deep learning technology, specifically generative artificial intelligence (GenAI) and natural language processing (NLP). Among the included 13 articles, most studies (84.6%) utilized secondary data analyses, primarily through GenAI/NLP. Nearly 77% of these studies were published in the past two years, with high quality of evidence. The primary focus areas were enhancing treatment and management, and timely OCD detection (both 38.5%); followed by AI tool development for broader mental health applications.</p><p><strong>Summary: </strong>AI technologies offer transformative potential for improvements related to OCD if diagnosis occurs earlier after onset; thereby lessening the consequential economic burden. Prioritizing investment in ethically sound AI research could significantly improve OCD outcomes in mental health care.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s40501-025-00359-8.</p>","PeriodicalId":11088,"journal":{"name":"Current Treatment Options in Psychiatry","volume":"12 1","pages":"23"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12167270/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Treatment Options in Psychiatry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40501-025-00359-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/14 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"Psychology","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: Obsessive-compulsive disorder (OCD) is a chronic and disabling condition, often leading to significant functional impairments. Despite its early onset, there is an average delay of 17 years from symptom onset to diagnosis and treatment, resulting in poorer outcomes. This systematic review aims to synthesize current findings on the application of AI in OCD, highlighting opportunities for early symptom detection, scalable therapy training, clinical decision support, novel therapeutics, computer vision-based approaches, and multimodal biomarker discovery.
Recent findings: While previous reviews focused on biomarker-based OCD detection and treatment using machine learning (ML), the findings of the current review add information about novel applications of deep learning technology, specifically generative artificial intelligence (GenAI) and natural language processing (NLP). Among the included 13 articles, most studies (84.6%) utilized secondary data analyses, primarily through GenAI/NLP. Nearly 77% of these studies were published in the past two years, with high quality of evidence. The primary focus areas were enhancing treatment and management, and timely OCD detection (both 38.5%); followed by AI tool development for broader mental health applications.
Summary: AI technologies offer transformative potential for improvements related to OCD if diagnosis occurs earlier after onset; thereby lessening the consequential economic burden. Prioritizing investment in ethically sound AI research could significantly improve OCD outcomes in mental health care.
Supplementary information: The online version contains supplementary material available at 10.1007/s40501-025-00359-8.
期刊介绍:
This journal focuses on the latest advances in the multifaceted treatment of psychiatric disorders. Designed for physicians and other mental health professionals, Current Treatment Options in Psychiatry offers expert reviews on the management of a range of mental health conditions, includingSchizophrenia and other psychotic disordersSubstance use disordersAnxiety, obsessive-compulsive, and related disordersMood disordersEating and other impulse control disordersPersonality disordersArticles cover a range of established and emerging treatment options across the lifespan, and their innovative, hands-on format makes them ideal for informing treatment decisions at the point of care.We accomplish this by appointing leaders in the field to serve as Section Editors in key areas. Section Editors, in turn, select the most pressing topics as well as experts to present the latest research, assess the efficacy of available treatment options, and discuss special considerations.Additionally, an international Editorial Board—representing a range of disciplines within psychiatry and psychology—ensures that the journal content includes current, emerging research and suggests articles of special interest to their country or region.