68 Ga-FAPI-04 PET Differentiates Benign From Malignant in a Patient With 18 F-FDG-Avid Colon Lesion.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-08-01 Epub Date: 2025-06-17 DOI:10.1097/RLU.0000000000005887

Na Qi, Haiyan Wang, Jie Ding, Jiangjun Jiang, Jun Zhao

引用次数: 0

Abstract

Lesions exhibiting heightened 18 F-FDG uptake in colorectal PET scans may be indicative of either benign or malignant processes, thus necessitating gastroscopic biopsy or pathologic assessment for diagnostic clarification. Herein, we reported intense 18 F-FDG uptake but negative 68 Ga-FAPI-04 PET uptake in a 65-year-old man with sigmoid colon tubular adenoma. This case underscores the utility of FAPI PET in preoperatively discerning between colorectal carcinoma and adenoma, potentially influencing treatment strategies.

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68Ga-FAPI-04 PET鉴别18f - fdg阳性结肠病变的良恶性

在结肠直肠PET扫描中显示18F-FDG摄取增高的病变可能指示良性或恶性病变，因此需要胃镜活检或病理评估来明确诊断。在本文中，我们报道了一位65岁的乙状结肠管状腺瘤患者强烈的18F-FDG摄取，但68Ga-FAPI-04 PET摄取阴性。本病例强调了FAPI PET在术前识别结直肠癌和腺瘤中的应用，可能影响治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.