FTIR Characterization and Bioactivity Assessment of Cinnamomum camphora Essential Oil: Antioxidant, Anti-Enzymatic, and Antifungal Properties Against Phytopathogens.

IF 2.3 3区化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Chemistry & Biodiversity Pub Date : 2025-06-16 DOI:10.1002/cbdv.202500720

Maroua Cheribot Cherif, Hicham Boughendjioua, Lucia Caputo, Ippolito Camele, Tarek Tahraoui, Vincenzo De Feo, Hazem S Elshafie

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引用次数: 0

Abstract

This study explores key biopharmaceutical properties of Cinnamomum camphora essential oil (EO), including antioxidant, anti-enzymatic, and antifungal activities, and evaluates its minimum inhibitory concentration (MIC) against some common phytopathogens. The functional groups of the EO were identified using Fourier-transform infrared (FTIR) spectroscopy. The antioxidant capacity, evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS, and ferric-reducing antioxidant power (FRAP) methods, revealed a moderate activity. The antifungal activity assay showed a complete growth inhibition of Monilinia laxa, Monilinia fructicola, Sclerotinia sclerotiorum, Colletotrichum gloeosporioides, and Botrytis cinerea at a concentration of 10 000 ppm of the tested EO. However, the lowest antifungal activity (17.8%) was observed against Aspergillus niger only at the highest tested concentration. The measured MIC was 7000 ppm for M. laxa and 8000 ppm for C. gloeosporioides. The anti-enzymatic activities of the studied EO demonstrated a low inhibitory effect on cholinesterases (AChE and BChE), but the EO exhibited inhibitory concentration (IC₅₀) values at 7.8 ± 0.6 and 2.78 ± 0.7 mg/mL for α-amylase and α-glucosidase, indicating a promising antidiabetic effect. This research revealed that the studied EO possesses various biological properties, indicating its potential applicability in several agro-pharmaceutical fields.

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香樟精油的FTIR表征和生物活性评价：抗氧化、抗酶和抗真菌对植物病原体的作用。

本研究探讨了香樟精油（Cinnamomum camphora精油）的主要生物制药特性，包括抗氧化、抗酶和抗真菌活性，并评估了其对一些常见植物病原体的最低抑制浓度（MIC）。利用傅里叶变换红外光谱（FTIR）鉴定了环氧乙烷的官能团。利用2,2-二苯基-1-苦味酰肼（DPPH）、ABTS和铁还原抗氧化能力（FRAP）方法对其抗氧化能力进行了评估，结果显示其抗氧化能力中等。抑菌活性测定结果表明，在10 000 ppm的浓度下，对松脂念珠菌、果念珠菌、菌核念珠菌、炭疽菌和灰葡萄孢菌均有完全的抑制作用。然而，只有在最高测试浓度下，对黑曲霉的抑菌活性最低（17.8%）。测得的MIC值分别为7000ppm和8000ppm。所研究的EO对胆碱酯酶（AChE和BChE）的抑制作用较低，但对α-淀粉酶和α-葡萄糖苷酶的抑制浓度（IC50）分别为7.8±0.6和2.78±0.7 mg/mL，具有良好的降糖作用。研究表明，所制备的EO具有多种生物学特性，表明其在多个农业制药领域具有潜在的应用前景。

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来源期刊

Chemistry & Biodiversity 环境科学-化学综合

CiteScore

3.40

自引率

10.30%

发文量

475

审稿时长

2.6 months

期刊介绍： Chemistry & Biodiversity serves as a high-quality publishing forum covering a wide range of biorelevant topics for a truly international audience. This journal publishes both field-specific and interdisciplinary contributions on all aspects of biologically relevant chemistry research in the form of full-length original papers, short communications, invited reviews, and commentaries. It covers all research fields straddling the border between the chemical and biological sciences, with the ultimate goal of broadening our understanding of how nature works at a molecular level. Since 2017, Chemistry & Biodiversity is published in an online-only format.