Accessing tetrasubstituted alkenes by co-catalyzed stereoselective hydrosilylation of 2,3-disubstituted 1,2-dienes

IF 6.5 1区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Catalysis Pub Date : 2025-06-16 DOI:10.1016/j.jcat.2025.116278

Ziwei Luo, Hao Zeng, Junyang Cen, Ze Li, Guo-Qiao Lai, Pinglu Zhang

引用次数: 0

Abstract

Tetrasubstituted alkene frameworks have been extensively employed in pharmaceuticals and material science, while their synthesis is of great challenging due to the uncontrolled Z/E selectivity. Here we would like to provide a novel and robust strategy to access a variety of tetrasubstituted alkenes via a cobalt-catalyzed stereoselective hydrosilylation of 2,3-disubstituted dienes. This study would like to provide a novel platform for fulfilling the map in construction of tetrasubstituted alkenes.

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2,3-二取代1,2-二烯共催化立体选择性硅氢化反应制备四取代烯烃

四取代烯烃框架广泛应用于制药和材料科学，但由于其不受控制的Z/E选择性，其合成具有很大的挑战性。在这里，我们希望提供一种新颖而强大的策略，通过钴催化2,3-二取代二烯的立体选择性硅氢化反应来获得各种四取代烯烃。本研究为实现四取代烯烃的结构图谱提供了一个新的平台

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Catalysis 工程技术-工程：化工

CiteScore

12.30

自引率

5.50%

发文量

447

审稿时长

31 days

期刊介绍： The Journal of Catalysis publishes scholarly articles on both heterogeneous and homogeneous catalysis, covering a wide range of chemical transformations. These include various types of catalysis, such as those mediated by photons, plasmons, and electrons. The focus of the studies is to understand the relationship between catalytic function and the underlying chemical properties of surfaces and metal complexes. The articles in the journal offer innovative concepts and explore the synthesis and kinetics of inorganic solids and homogeneous complexes. Furthermore, they discuss spectroscopic techniques for characterizing catalysts, investigate the interaction of probes and reacting species with catalysts, and employ theoretical methods. The research presented in the journal should have direct relevance to the field of catalytic processes, addressing either fundamental aspects or applications of catalysis.