Large Stokes shift by increasing intramolecular charge transfer for high signal-to-background ratio bioimaging

IF 4.3 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-06-17 DOI:10.1039/d5cc02608c

Shiyu Wu, Zhicheng Ban, Hui Tang, Ning Ma, Xiaoyun Ran, Qian Zhou, Yahui Zhang, Zhouyu Wang, Xiaoqi Yu

引用次数: 0

Abstract

Novel bicyclic 2-pyridone probes with strong electron donors (from Br in cDHIP-N-Br to dimethoxytriphenylamine in cDHIP-N-MTPA) exhibit redshifted emission (535–759 nm) and large Stokes shifts (≤320 nm) due to ICT effects, enabling high-contrast bioimaging in cells, tumor spheroids, and mice, showcasing their potential for advanced fluorescence imaging.

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通过增加分子内电荷转移来实现高信号背景比生物成像的大斯托克斯位移

新型双环2-吡啶酮探针具有强电子给体（从cd髋关节- n -Br中的Br到cd髋关节- n - mtpa中的二甲氧基三苯胺），由于ICT效应，具有红移发射（535-759 nm）和大Stokes位移（≤320 nm），能够在细胞、肿瘤球体和小鼠中实现高对比度生物成像，显示出它们在高级荧光成像方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.