Tushar Sharma, Bhavina Sharma, Rahul Chaudhary, Nauder Faraday, Andrew M Goldsweig
{"title":"Coronary Artery Disease and Human Immunodeficiency Virus.","authors":"Tushar Sharma, Bhavina Sharma, Rahul Chaudhary, Nauder Faraday, Andrew M Goldsweig","doi":"10.1016/j.cpcardiol.2025.103101","DOIUrl":null,"url":null,"abstract":"<p><p>Cardiac complications in individuals infected with the human immunodeficiency virus (HIV) have been recognized since the 1980s. However, the type of cardiac conditions seen in this population has changed substantially since the introduction of antiretroviral therapy (ART). Coronary artery disease (CAD) has emerged as a leading cause of morbidity and mortality in HIV positive individuals. HIV and ART have both been linked to the development of CAD through multiple mechanisms. There is limited specific guidance for management of CAD and its risk factors in people with HIV. This literature review explores the pathophysiology and management of CAD in HIV-infected patients, identifying gaps in evidence and areas for future research to address the growing burden of CAD in this patient population.</p>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":" ","pages":"103101"},"PeriodicalIF":3.0000,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Problems in Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.cpcardiol.2025.103101","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Cardiac complications in individuals infected with the human immunodeficiency virus (HIV) have been recognized since the 1980s. However, the type of cardiac conditions seen in this population has changed substantially since the introduction of antiretroviral therapy (ART). Coronary artery disease (CAD) has emerged as a leading cause of morbidity and mortality in HIV positive individuals. HIV and ART have both been linked to the development of CAD through multiple mechanisms. There is limited specific guidance for management of CAD and its risk factors in people with HIV. This literature review explores the pathophysiology and management of CAD in HIV-infected patients, identifying gaps in evidence and areas for future research to address the growing burden of CAD in this patient population.
期刊介绍：
Under the editorial leadership of noted cardiologist Dr. Hector O. Ventura, Current Problems in Cardiology provides focused, comprehensive coverage of important clinical topics in cardiology. Each monthly issues, addresses a selected clinical problem or condition, including pathophysiology, invasive and noninvasive diagnosis, drug therapy, surgical management, and rehabilitation; or explores the clinical applications of a diagnostic modality or a particular category of drugs. Critical commentary from the distinguished editorial board accompanies each monograph, providing readers with additional insights. An extensive bibliography in each issue saves hours of library research.
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