Sofia A Finestone, Liara S Ortiz-Ocasio, Arjun Shetty, Brandon Boyarsky, Stephanie Vu, Nicole A Derdzakyan, Md Sohel Rana, Gary F Rogers, Albert K Oh
{"title":"Rib Autograft Versus Porous Polyethylene Implant Outcomes in Microtia Reconstruction: A Meta-Analysis and Systematic Review.","authors":"Sofia A Finestone, Liara S Ortiz-Ocasio, Arjun Shetty, Brandon Boyarsky, Stephanie Vu, Nicole A Derdzakyan, Md Sohel Rana, Gary F Rogers, Albert K Oh","doi":"10.1177/10556656251349274","DOIUrl":null,"url":null,"abstract":"<p><p>ObjectiveAuricular reconstruction for microtia typically involves autologous rib cartilage graft (ARCG) or porous polyethylene (PPE) implants. While ARCG is considered the gold standard, PPE has shown elimination of donor site morbidity. This meta-analysis compares outcomes between ARCG and PPE implants.DesignA systematic search of literature from 2000 to 2023 identified 3463 studies. Cohorts and large case series comparing ARCG to PPE were included. Meta-analysis calculated pooled effect size differences in microtia reconstruction outcomes using a random-effects model.Main Outcome MeasuresPrimary outcomes included infection rates, framework exposure, and redo procedures. Secondary outcomes assessed aesthetic results, patient satisfaction, and quality of life.ResultsEleven studies met inclusion criteria, accounting for 3816 patients. Follow-up ranged from 30 days to 11 years for ARCG and 30 days to 8 years for PPE. Meta-analysis revealed that PPE had higher pooled infection, framework exposure, and redo operation rate differences of 3.18% (95% confidence interval [CI]: -2.00, 8.36%), 6.97% (95% CI: 0.07, 13.86%), and 4.88% (95% CI: -3.45, 13.20%), respectively. Moderate-to-significant heterogeneity was found (<i>I</i><sup>2</sup> = 39%-68%). Aesthetic outcomes and patient satisfaction varied, with 1 study reporting higher satisfaction with PPE (90% vs 47.1% for ARCG), while a larger study found greater satisfaction with ARCG (95.3% vs 82.7% for PPE). No significant differences were found in quality of life.ConclusionPPE implants may be associated with higher rates of infection, framework exposure, and redo procedures compared to ARCG. Poor study quality and heterogeneity highlight the need for further research comparing these techniques.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251349274"},"PeriodicalIF":1.1000,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cleft Palate-Craniofacial Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/10556656251349274","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0
Abstract
ObjectiveAuricular reconstruction for microtia typically involves autologous rib cartilage graft (ARCG) or porous polyethylene (PPE) implants. While ARCG is considered the gold standard, PPE has shown elimination of donor site morbidity. This meta-analysis compares outcomes between ARCG and PPE implants.DesignA systematic search of literature from 2000 to 2023 identified 3463 studies. Cohorts and large case series comparing ARCG to PPE were included. Meta-analysis calculated pooled effect size differences in microtia reconstruction outcomes using a random-effects model.Main Outcome MeasuresPrimary outcomes included infection rates, framework exposure, and redo procedures. Secondary outcomes assessed aesthetic results, patient satisfaction, and quality of life.ResultsEleven studies met inclusion criteria, accounting for 3816 patients. Follow-up ranged from 30 days to 11 years for ARCG and 30 days to 8 years for PPE. Meta-analysis revealed that PPE had higher pooled infection, framework exposure, and redo operation rate differences of 3.18% (95% confidence interval [CI]: -2.00, 8.36%), 6.97% (95% CI: 0.07, 13.86%), and 4.88% (95% CI: -3.45, 13.20%), respectively. Moderate-to-significant heterogeneity was found (I2 = 39%-68%). Aesthetic outcomes and patient satisfaction varied, with 1 study reporting higher satisfaction with PPE (90% vs 47.1% for ARCG), while a larger study found greater satisfaction with ARCG (95.3% vs 82.7% for PPE). No significant differences were found in quality of life.ConclusionPPE implants may be associated with higher rates of infection, framework exposure, and redo procedures compared to ARCG. Poor study quality and heterogeneity highlight the need for further research comparing these techniques.
期刊介绍:
The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.