Comparing Myopia Control Effects of Three Different Orthokeratology Lenses and Spectacle Lenses With Highly Aspherical Lenslets in Low Myopia Children.

IF 2.6 3区 医学 Q2 OPHTHALMOLOGY
Na Li, Luodian Luobu, Bei Du, Weiping Lin, Ruihua Wei
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Abstract

Purpose: To compare the effectiveness of three different orthokeratology (OK) lenses and highly aspherical-lenslet spectacle lenses (HAL) for myopia control in young children with low myopia, and to compare the relative corneal refractive power (RCRP) distributions among the three OK lenses with different designs.

Methods: This retrospective study involved 166 children aged eight to 11 years with myopia of -0.50 to -3.00 D treated with ProTong OK lenses with aspheric base curve (APOK), ProTong OK lenses with spherical base curve (SPOK), Euclid OK lenses (EOK), HAL, or single-vision spectacle lenses (SVL). Axial length (AL) was measured at baseline and the 12-month visit. Corneal topography was measured for OK wearers to determine the distance from the apex RCRP profile to its three-quarter-peak.

Results: The axial elongation for the APOK, SPOK, HAL, EOK, and SVL groups were 0.17 ± 0.14 mm, 0.25 ± 0.17 mm, 0.11 ± 0.15 mm, 0.37 ± 0.12 mm, and 0.45 ± 0.16 mm after 12 months, respectively. Axial elongation was significantly slower for the APOK, SPOK, and HAL groups than for the EOK or SVL groups (all P < 0.05); and it was significantly slower in HAL than in SPOK wearers (P < 0.05). 59.5% and 42.9% of HAL and APOK wearers experienced axial elongation of ≤0.15 mm, respectively. The HAL and APOK, SPOK and APOK, or EOK and SVL groups showed no significant differences in axial elongation. Both SPOK and APOK groups had lower 3/4X values than the EOK group.

Conclusions: HAL and APOK wear, relative to EOK or SVL wear, by eight- to 11-year-old children with low myopia led to comparable yet slower axial elongation. APOK and SPOK led to a steeper distribution of the RCRP profile within the pupillary range and yielded better myopia control than EOK.

Translational relevance: HAL and APOK are recommended for effective myopia control in children aged eight to 11 years with mild myopia.

三种不同角膜塑形镜与高度非球面眼镜对低近视儿童近视控制效果的比较。
目的:比较三种不同的角膜塑形镜(OK)和高度非球面晶状体眼镜(HAL)对低度近视儿童近视控制的效果,并比较三种不同设计的OK镜的相对角膜屈光度(RCRP)分布。方法:对166例8 ~ 11岁近视-0.50 ~ -3.00 D的儿童进行回顾性研究,分别采用非球面波通OK晶状体(APOK)、球面波通OK晶状体(SPOK)、欧氏OK晶状体(EOK)、HAL或单视力镜片(SVL)。在基线和12个月随访时测量轴向长度(AL)。对OK佩戴者的角膜地形图进行测量,以确定从RCRP曲线顶点到其四分之三峰值的距离。结果:APOK、SPOK、HAL、EOK、SVL组12个月后的轴向伸长率分别为0.17±0.14 mm、0.25±0.17 mm、0.11±0.15 mm、0.37±0.12 mm、0.45±0.16 mm。APOK、SPOK和HAL组的轴向伸长明显慢于EOK和SVL组(均P < 0.05);HAL组明显慢于SPOK组(P < 0.05)。HAL和APOK佩戴者的轴向伸长率分别为59.5%和42.9%。HAL组与APOK组、SPOK组与APOK组、EOK组与SVL组轴向伸长无显著差异。SPOK组和APOK组的3/4X值均低于EOK组。结论:8 - 11岁低近视儿童佩戴HAL和APOK,相对于佩戴EOK或SVL,可导致相对较慢的轴向伸长。与EOK相比,APOK和SPOK使RCRP在瞳孔范围内的分布更陡,对近视的控制效果更好。翻译相关性:HAL和APOK推荐用于8 - 11岁轻度近视儿童的有效近视控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Translational Vision Science & Technology
Translational Vision Science & Technology Engineering-Biomedical Engineering
CiteScore
5.70
自引率
3.30%
发文量
346
审稿时长
25 weeks
期刊介绍: Translational Vision Science & Technology (TVST), an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purpose is to advance research worldwide into understanding the visual system and preventing, treating and curing its disorders, is an online, open access, peer-reviewed journal emphasizing multidisciplinary research that bridges the gap between basic research and clinical care. A highly qualified and diverse group of Associate Editors and Editorial Board Members is led by Editor-in-Chief Marco Zarbin, MD, PhD, FARVO. The journal covers a broad spectrum of work, including but not limited to: Applications of stem cell technology for regenerative medicine, Development of new animal models of human diseases, Tissue bioengineering, Chemical engineering to improve virus-based gene delivery, Nanotechnology for drug delivery, Design and synthesis of artificial extracellular matrices, Development of a true microsurgical operating environment, Refining data analysis algorithms to improve in vivo imaging technology, Results of Phase 1 clinical trials, Reverse translational ("bedside to bench") research. TVST seeks manuscripts from scientists and clinicians with diverse backgrounds ranging from basic chemistry to ophthalmic surgery that will advance or change the way we understand and/or treat vision-threatening diseases. TVST encourages the use of color, multimedia, hyperlinks, program code and other digital enhancements.
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