Diagnosis of infantile subglottic hemangioma: a 10-year experience of 25 cases.

IF 2.1 3区医学 Q2 PEDIATRICS

Frontiers in Pediatrics Pub Date : 2025-05-30 eCollection Date: 2025-01-01 DOI:10.3389/fped.2025.1499656

Xiaoben Liang, Rong Xu, Hongming Xu, Jiarui Chen, Xiaoyan Li

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引用次数: 0

Abstract

Objectives: This study aims to explore the clinical appearances of infantile subglottic hemangioma (SGH) and the diagnostic value of flexible fiberoptic laryngoscopy (FFL) combined with contrast-enhanced CT (CECT).

Methods: We retrospectively analyzed the data of 25 children diagnosed with SGH from January 2012 to January 2022.

Results: FFL showed a smooth, rounded, vascular-appearing submucosal lesion in the subglottic wall, while CECT revealed an enhancing lesion, obscuring the airway lumen. Among the 25 cases (8 males and 17 females; 10 left-sided, 11 right-sided, and 4 middle), the clinical appearances contained stridor (25), respiratory distress (13), three-concave sign (10), barking cough (9), feeding difficulty (8), cyanosis (2), and hoarseness (2). SGH with cutaneous hemangiomas accounted for 24% (6/25). The age at presentation ranged from 1 day to 8 months (median, 33 days), including 96% (24/25) of cases aged <6 months. Moreover, 92% (23/25) of cases had a history of misdiagnosis, 22 respiratory infections, 5 laryngomalacia, 1 laryngeal cyst, and 1 asthma, individually or in combination. Except for one case that died of polygenic abnormality and another case lost to follow-up, the remaining 23 cases were cured after oral propranolol.

Conclusions: For an infant with respiratory symptoms, who has repeated condition or poor effect after routine treatment, SGH should be considered, especially in infants under 6 months old. FFL combined with CECT is recommended to make a definite diagnosis of SGH.

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婴儿声门下血管瘤的诊断：10年25例的经验。

目的：探讨小儿声门下血管瘤（SGH）的临床表现及软性纤维喉镜（FFL）联合增强CT （CECT）的诊断价值。方法：回顾性分析2012年1月至2022年1月诊断为SGH的25例儿童的资料。结果：FFL显示声门下壁粘膜下病变光滑，圆形，血管状，而CECT显示强化病变，模糊气道管腔。25例患者中，男8例，女17例；左侧10例，右侧11例，中部4例)，临床表现为喘鸣（25例），呼吸窘迫（13例），三凹征（10例），吠叫咳嗽（9例），喂养困难（8例），发绀（2例），声音嘶哑（2例）。SGH合并皮肤血管瘤占24%（6/25）。96%（24/25）的病例年龄在1天至8个月（中位33天）之间，结论：对于有呼吸道症状的婴儿，常规治疗后病情反复或效果不佳，应考虑SGH，特别是6个月以下的婴儿。建议FFL联合CECT对SGH进行明确诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health

CiteScore

3.60

自引率

7.70%

发文量

2132

审稿时长

14 weeks

期刊介绍： Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.