Deep learning-driven approach for cataract management: towards precise identification and predictive analytics.

IF 4.6 2区 生物学 Q2 CELL BIOLOGY
Frontiers in Cell and Developmental Biology Pub Date : 2025-05-30 eCollection Date: 2025-01-01 DOI:10.3389/fcell.2025.1611216
Shuaixin Lu, Lingling Ba, Jie Wang, Min Zhou, Peiyao Huang, Xiaohua Zhang, Simo Pan, Xinmiao Zhou, Kai Wen, Jing Sun
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引用次数: 0

Abstract

Deep learning (DL) technology has shown significant potential in the whole process of cataract diagnosis and treatment through algorithms such as convolutional neural network (CNN). In terms of diagnosis, DL models based on fundus or slit-lamp images can automatically identify and grade cataract, and their diagnostic accuracy is close to or beyond the level of human experts. In the field of surgery, DL can analyze the operation video stage in real time, accurately track the instruments and optimize the operation process, and reduce the risk of intraoperative eye error through intelligent devices. DL could optimize the intraocular lens (IOL) power calculation, predict the risk of complications and long-term surgery requirements. However, insufficient data standardization, the "black box" characteristics of the model, and privacy ethics issues are still the bottlenecks in clinical application. In the future, it is necessary to improve the generalization ability of model through multimodal data fusion, federated learning and other technologies, and combine interpretable design (such as Grad-CAM) to promote the evolution of DL to a transparent medical decision-making tool, and finally realize the intelligence and universality of cataract management.

白内障管理的深度学习驱动方法:走向精确识别和预测分析。
深度学习(DL)技术通过卷积神经网络(CNN)等算法,在白内障诊疗的全过程中显示出巨大的潜力。在诊断方面,基于眼底或裂隙灯图像的DL模型可以自动识别和分级白内障,其诊断准确率接近或超过人类专家的水平。在手术领域,DL可以实时分析手术视频阶段,准确跟踪器械并优化手术流程,通过智能设备降低术中眼误风险。DL可以优化人工晶状体(IOL)度数计算,预测并发症风险和远期手术需求。然而,数据标准化程度不高、模型的“黑箱”特征以及隐私伦理问题仍然是临床应用的瓶颈。未来需要通过多模态数据融合、联邦学习等技术提高模型的泛化能力,并结合可解释性设计(如gradm - cam),推动深度学习向透明的医疗决策工具演进,最终实现白内障管理的智能化和普用化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology Biochemistry, Genetics and Molecular Biology-Cell Biology
CiteScore
9.70
自引率
3.60%
发文量
2531
审稿时长
12 weeks
期刊介绍: Frontiers in Cell and Developmental Biology is a broad-scope, interdisciplinary open-access journal, focusing on the fundamental processes of life, led by Prof Amanda Fisher and supported by a geographically diverse, high-quality editorial board. The journal welcomes submissions on a wide spectrum of cell and developmental biology, covering intracellular and extracellular dynamics, with sections focusing on signaling, adhesion, migration, cell death and survival and membrane trafficking. Additionally, the journal offers sections dedicated to the cutting edge of fundamental and translational research in molecular medicine and stem cell biology. With a collaborative, rigorous and transparent peer-review, the journal produces the highest scientific quality in both fundamental and applied research, and advanced article level metrics measure the real-time impact and influence of each publication.
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