{"title":"Analytical Methods Developed for the Determination of Pantoprazole Sodium: Overview.","authors":"Aysen Kurt Cucu","doi":"10.1080/10408347.2025.2516603","DOIUrl":null,"url":null,"abstract":"<p><p>Pantoprazole sodium a substituted benzimidazole derivative is an irreversible proton pump inhibitor and was developed for the treatment of acid-related gastrointestinal disorders. As with other drugs of its class (omeprazol or lansoprazole), pantoprazole reduces gastric acid secretion through inhibition of the portion on the gastric parietal cell. Analytical methods for the determination of the active drug ingredient pantoprazole sodium are available in many manuscripts. Pantoprazole sodium, alone or in combination with other drugs, in different pharmaceutical forms, industrial wastewater, and plasma samples using spectroscopic, chromatographic, electroanalytical and thermal analysis methods have been made by many researchers analyzed. Manuscripts were identified that included analytic methods developed to analyze pantoprazole sodium alone or in the presence of other drugs included. In this review, an overview of the analytical methods developed for the determination of Pantoprazole sodium and their validation will be given.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":" ","pages":"1-31"},"PeriodicalIF":5.2000,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Critical reviews in analytical chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/10408347.2025.2516603","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Pantoprazole sodium a substituted benzimidazole derivative is an irreversible proton pump inhibitor and was developed for the treatment of acid-related gastrointestinal disorders. As with other drugs of its class (omeprazol or lansoprazole), pantoprazole reduces gastric acid secretion through inhibition of the portion on the gastric parietal cell. Analytical methods for the determination of the active drug ingredient pantoprazole sodium are available in many manuscripts. Pantoprazole sodium, alone or in combination with other drugs, in different pharmaceutical forms, industrial wastewater, and plasma samples using spectroscopic, chromatographic, electroanalytical and thermal analysis methods have been made by many researchers analyzed. Manuscripts were identified that included analytic methods developed to analyze pantoprazole sodium alone or in the presence of other drugs included. In this review, an overview of the analytical methods developed for the determination of Pantoprazole sodium and their validation will be given.
期刊介绍：
Critical Reviews in Analytical Chemistry continues to be a dependable resource for both the expert and the student by providing in-depth, scholarly, insightful reviews of important topics within the discipline of analytical chemistry and related measurement sciences. The journal exclusively publishes review articles that illuminate the underlying science, that evaluate the field''s status by putting recent developments into proper perspective and context, and that speculate on possible future developments. A limited number of articles are of a "tutorial" format written by experts for scientists seeking introduction or clarification in a new area.
This journal serves as a forum for linking various underlying components in broad and interdisciplinary means, while maintaining balance between applied and fundamental research. Topics we are interested in receiving reviews on are the following:
· chemical analysis;
· instrumentation;
· chemometrics;
· analytical biochemistry;
· medicinal analysis;
· forensics;
· environmental sciences;
· applied physics;
· and material science.
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