Point-of-Care Photoresistive and Colorimetric Sensor for Iron Detection in Environmental and Biological Samples with Spectroscopic Validation.

IF 3.5 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
Shrikant Kashyap, Purushotam Shivshakti Mahan, Harendra Singh, Sibnath Kayal, Tapas K Mandal
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引用次数: 0

Abstract

The development of an innovative, selective, and portable digital photoresistive sensor for sensing iron in the environment and biological samples is reported in this article. Colorimetric sensing of the analyte is investigated, akin to the spectrophotometric absorption principle. Iron in the sample is measured by the formation of orange-colored ferroin resulting from the 1,10-phenanthroline reaction. The reaction scheme is designed to be pH-specific, simple, quick, and effective in detecting trace amounts of iron in real sample matrices without employing any tedious route of synthesis and its characterization. A digital photoresistive prototype is fabricated using a light-emitting diode (LED) and a light-dependent resistor (LDR) to measure the concentration of iron much less than the recommended value by the World Health Organization (WHO). The limit of detection (LOD) is reported to be 0.017 mg L-1, the lowest to date for the class of point of care (POC) devices. The sensor was tested on 55 real-life samples and exhibited good accuracy with UV-vis and AAS measurements with an average absolute % error of 3.258%-14.34%. The present prototype promises to be a user-friendly, cost-effective solution to the pressing need of monitoring iron for the environment and healthcare sector.

用于环境和生物样品中铁检测的即时光敏比色传感器与光谱验证。
本文报道了一种创新的、选择性的、便携式数字光敏传感器的发展,用于检测环境和生物样品中的铁。分析物的比色感应被研究,类似于分光光度吸收原理。样品中的铁是通过1,10-菲罗啉反应生成的橙色铁蛋白来测定的。该反应方案设计为ph特异性,简单,快速,有效地检测实际样品基质中的痕量铁,而无需采用任何繁琐的合成路线及其表征。利用发光二极管(LED)和依赖于光的电阻器(LDR)制作了一个数字光敏样机,以测量远低于世界卫生组织(WHO)推荐值的铁浓度。据报道,检出限(LOD)为0.017 mg L-1,是迄今为止护理点(POC)设备类的最低检出限。该传感器在55个实际样品上进行了测试,具有良好的紫外可见和原子吸收光谱测量精度,平均绝对误差为3.258% ~ 14.34%。目前的原型有望成为一种用户友好、成本效益高的解决方案,以满足环境和医疗保健部门对铁监测的迫切需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chemistry - An Asian Journal
Chemistry - An Asian Journal 化学-化学综合
CiteScore
7.00
自引率
2.40%
发文量
535
审稿时长
1.3 months
期刊介绍: Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).
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