The IDEAL framework for machine perfusion in liver transplantation

IF 45.9 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Nature Reviews Gastroenterology &Hepatology Pub Date : 2025-06-16 DOI:10.1038/s41575-025-01085-5

Otto B. van Leeuwen, David Nasralla, Carlo D. L. Ceresa, Philipp Dutkowski, Peter J. Friend, Gabriel C. Oniscu, Robert J. Porte, Vincent E. de Meijer

引用次数: 0

Abstract

Liver transplantation is challenged by organ scarcity and ageing donors. Machine perfusion is a promising technique to enhance organ preservation and assessment, improving liver utilization and patient outcomes. Here, we discuss current practices in machine perfusion using the IDEAL framework and outline the steps needed to advance this technology clinically.

Abstract Image

查看原文本刊更多论文

肝移植机器灌注的IDEAL框架

肝移植受到器官短缺和供体老化的挑战。机器灌注是一种很有前途的技术，可以加强器官保存和评估，提高肝脏利用率和患者预后。在这里，我们讨论了目前使用IDEAL框架的机器灌注实践，并概述了临床推进该技术所需的步骤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature Reviews Gastroenterology &Hepatology 医学-胃肠肝病学

CiteScore

52.30

自引率

0.60%

发文量

147

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication. The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information. Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.