Sexual functioning after vaginal natural orifice transluminal endoscopic surgery: combined results of two randomized controlled trials.

IF 3.3 3区 医学 Q1 UROLOGY & NEPHROLOGY
Sofia Prekatsounaki, Jan J A Bosteels, Jan F Baekelandt, Ben W J Mol, Paul Enzlin
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引用次数: 0

Abstract

Objective: To explore women's sexual functioning and associated quality of life after vaginal natural orifice transluminal endoscopic surgery (vNOTES) as an alternative to laparoscopy.

Design: Two parallel group, 1:1 randomized single-centre single-blinded trials comparing the effects of vNOTES and laparoscopy.

Setting: Gynaecology unit of a Belgian teaching hospital.

Population: Women aged between 18 and 70 years with a benign indication for hysterectomy or adnexectomy.

Methods: After informed consent, women were randomized for vNOTES (experimental group) or laparoscopy (control group). Participants and outcome assessors were blinded. Paper and pencil questionnaires before surgery, as well as at 3 and 6 months after surgery.

Main outcome measures: The outcome of interest in this secondary analysis was sexual functioning at 3 and 6 months after surgery. We additionally measured quality of life.

Results: We studied 68 women allocated to the vNOTES (experimental) condition and 67 women allocated to the laparoscopy (control) condition. No significant effects of time, type of surgery, and surgical technique were found on patients' sexual function. At 3 and 6 months post-surgery, an increasing number of negative associations were found between quality of life and aspects of sexual functioning.

Conclusions: vNOTES applied for hysterectomy and adnexectomy as compared to laparoscopy does not have a differential impact on women's sexual functioning. Sexual function has few links to patients' quality of life before surgery, but grows in relevance as a negative correlate of quality of life after surgery.

阴道自然孔腔内窥镜手术后的性功能:两项随机对照试验的综合结果。
目的:探讨阴道自然口腔内内镜手术(vNOTES)替代腹腔镜手术对女性性功能及相关生活质量的影响。设计:两个平行组,1:1随机单中心单盲试验,比较vNOTES和腹腔镜的效果。单位:比利时教学医院妇科。人群:年龄在18 - 70岁之间,有良性子宫切除或附件切除指征的女性。方法:经知情同意后,将女性随机分为vNOTES组(实验组)和腹腔镜组(对照组)。参与者和结果评估者采用盲法。术前及术后3、6个月用纸笔问卷调查。主要结局指标:在这个次要分析中感兴趣的结果是术后3个月和6个月的性功能。我们还测量了他们的生活质量。结果:我们研究了68名妇女分配到vNOTES(实验)条件和67名妇女分配到腹腔镜(对照)条件。手术时间、手术类型和手术技术对患者性功能无明显影响。在术后3至6个月,越来越多的负面关联被发现存在于生活质量和性功能之间。结论:vNOTES应用于子宫和附件切除术与腹腔镜相比,对女性性功能的影响没有差异。性功能与患者术前生活质量的关系不大,但与术后生活质量的负相关关系日益密切。
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来源期刊
Journal of Sexual Medicine
Journal of Sexual Medicine 医学-泌尿学与肾脏学
CiteScore
6.20
自引率
5.70%
发文量
826
审稿时长
2-4 weeks
期刊介绍: The Journal of Sexual Medicine publishes multidisciplinary basic science and clinical research to define and understand the scientific basis of male, female, and couples sexual function and dysfunction. As an official journal of the International Society for Sexual Medicine and the International Society for the Study of Women''s Sexual Health, it provides healthcare professionals in sexual medicine with essential educational content and promotes the exchange of scientific information generated from experimental and clinical research. The Journal of Sexual Medicine includes basic science and clinical research studies in the psychologic and biologic aspects of male, female, and couples sexual function and dysfunction, and highlights new observations and research, results with innovative treatments and all other topics relevant to clinical sexual medicine. The objective of The Journal of Sexual Medicine is to serve as an interdisciplinary forum to integrate the exchange among disciplines concerned with the whole field of human sexuality. The journal accomplishes this objective by publishing original articles, as well as other scientific and educational documents that support the mission of the International Society for Sexual Medicine.
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