The effect of the prognostic nutritional index in the first trimester on birth weight: A retrospective study

IF 1.6 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research Pub Date : 2025-06-15 DOI:10.1111/jog.16341

Arife Akay, Yıldız Akdaş-Reis, Khurshud Hajıyeva, Neval Çayonu-Kahraman, Yaprak Engin-Üstün

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引用次数: 0

Abstract

Aim

The study aimed to investigate the effect of the maternal prognostic nutritional index (PNI) in the first trimester on birth weight.

Methods

This retrospective study was conducted on term births between 2015 and 2022. The subjects were classified into three categories based on their birth weight: small gestational age (SGA), adequate gestational age (AGA), and large gestational age (LGA). The values of PNI, albumin (ALB), and hemoglobin (HB) were determined in the first trimester. PNI, ALB, and HB levels, demographic, obstetric, and neonatal outcomes were compared in the three groups.

Results

A total of 302 singleton pregnancies were included, with 79 cases classified as SGA (26.2%), 147 cases as AGA (48.6%), and 76 cases as LGA (25.2%). The mean ages and body mass index (BMI) of the groups were found to be similar (p < 0.05). HB (12.3 ± 1.28 g/dL), ALB (3.5 ± 0.37 g/dL), and PNI (35.7 ± 3.78) levels were found to be lower in the SGA group (p < 0.05). The cut-off values for ALB and PNI were 3.5 g/dL and 35, respectively (80.3% and 81% sensitivity and 54.4% specificity). A positive correlation was identified between the 1 min Apgar score and both ALB and PNI (p = 0.002, r = 0.176).

Discussion

A reduction in PNI, HB, and ALB levels was observed in the SGA group, whereas no significant difference was identified in the LGA group. To achieve an adequate birth weight, it is recommended that the nutritional status and anemia of the mother be improved before and during pregnancy.

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妊娠早期预后营养指数对出生体重的影响：一项回顾性研究

目的探讨妊娠早期产妇预后营养指数（PNI）对新生儿出生体重的影响。方法对2015 ~ 2022年足月分娩的孕妇进行回顾性研究。根据出生体重将受试者分为小胎龄（SGA）、足胎龄（AGA）和大胎龄（LGA）三类。在妊娠早期测定PNI、白蛋白（ALB）和血红蛋白（HB）的值。比较三组的PNI、ALB和HB水平、人口统计学、产科和新生儿结局。结果共纳入302例单胎妊娠，其中SGA 79例（26.2%），AGA 147例（48.6%），LGA 76例（25.2%）。各组的平均年龄和体重指数（BMI）相似（p < 0.05）。SGA组HB（12.3±1.28 g/dL）、ALB（3.5±0.37 g/dL）、PNI（35.7±3.78）水平降低（p < 0.05）。ALB和PNI的临界值分别为3.5 g/dL和35 g/dL（敏感性80.3%和81%，特异性54.4%）。1 min Apgar评分与ALB、PNI均呈正相关（p = 0.002, r = 0.176）。在SGA组中观察到PNI、HB和ALB水平的降低，而在LGA组中没有发现显著差异。为了获得足够的出生体重，建议在怀孕前和怀孕期间改善母亲的营养状况和贫血。

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来源期刊

Journal of Obstetrics and Gynaecology Research 医学-妇产科学

CiteScore

3.10

自引率

0.00%

发文量

376

审稿时长

3-6 weeks

期刊介绍： The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology. The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.