Composition and medicinal applications of Citrus essential oils: Current insights and future perspectives

Q3 Pharmacology, Toxicology and Pharmaceutics

Phytomedicine Plus Pub Date : 2025-06-09 DOI:10.1016/j.phyplu.2025.100836

Farah Aprisza Sheelmarevaa , Pramesthi Reitza Navisya Vasall , Nandang Permadi , Asep Harja , Sarifah Nurjanah , Jamaludin Al-Anshori , Euis Julaeha

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Abstract

Citrus essential oils (CEOs) are volatile aromatic compounds derived from various plant structures, such as peels, leaves, flowers, and seeds, with unique chemical compositions influenced by species, climate, and extraction methods. CEOs, rich in terpenes and terpenoids, exhibit diverse biological activities, including antimicrobial, antioxidant, and anti-inflammatory properties. These oils have shown significant potential in combating infectious diseases and preserving food, alongside applications in the pharmaceutical, cosmetic, and perfume industries. This review summarizes current knowledge on CEOs' using PRISMA methodology focusing in chemical composition and biological activities, emphasizing their medicinal applications, such as anticancer and antimicrobial activities, and the mechanisms underlying their effects. In addition, it evaluates the benefits and challenges of their use in modern medical settings, highlighting their potential as natural agents for enhancing public health.

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柑橘精油的成分和药用：当前的见解和未来的观点

柑橘精油（ceo）是从各种植物结构中提取的挥发性芳香化合物，如果皮、叶子、花和种子，具有独特的化学成分，受物种、气候和提取方法的影响。黄芪富含萜烯和萜类化合物，具有多种生物活性，包括抗菌、抗氧化和抗炎特性。这些油在对抗传染病和保存食品方面显示出巨大的潜力，同时在制药、化妆品和香水工业中也有应用。本文综述了目前利用PRISMA方法对其化学成分和生物活性的研究进展，重点介绍了其抗癌和抗菌等药用应用及其作用机制。此外，它还评估了在现代医疗环境中使用它们的好处和挑战，强调了它们作为促进公众健康的天然制剂的潜力。

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