Advancements in metal oxide-based innovative nanomaterials for biomedical applications: Challenges and future outlook

IF 2.7 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Letters Pub Date : 2025-06-11 DOI:10.1016/j.matlet.2025.138912

Khushboo Gupta , Sunil Chauhan , Dharm Veer Singh , V.E.A. Montaño , O.P. Thakur , Santosh Kumar , Rajesh Dhiman , O.Raymond Herrera , Manish Kumar , Subhash Sharma

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引用次数: 0

Abstract

Numerous researchers have been interested in nanomaterials due to their small size, great stability, affinity, and selectivity. Numerous metal and metal-oxide nanomaterials (MONMs) have been the subject of extensive, intensive research over the past few decades due to their important characteristics, which include size, shape, surface mass proportion, and reactivity. Antimicrobial therapy, targeted drug delivery, magnetic resonance imaging (MRI), and cancer treatment are just a few of the areas in which the nanoparticles (NPs) are being used. MONMs can fight against antibiotic-resistant bacteria by disrupting cell walls, offering controlled drug delivery to targeted tissues, enhancing MRI contrast for better disease diagnosis, and delivering chemotherapy directly to tumors/cancer, minimizing side effects. Despite challenges related to toxicity and stability, MONMs in improving medical treatments make these NPs a game-changing solution for tackling critical issues like antibiotic resistance and enhancing diagnostic and therapeutic efficacy in modern healthcare.

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生物医学应用金属氧化物基创新纳米材料的进展：挑战与未来展望

纳米材料具有体积小、稳定性好、亲和性强、选择性高等特点，引起了众多研究人员的兴趣。在过去的几十年里，许多金属和金属氧化物纳米材料（MONMs）由于其重要的特性，包括尺寸、形状、表面质量比例和反应性，已经成为广泛而深入研究的主题。抗菌治疗、靶向药物递送、磁共振成像（MRI）和癌症治疗只是纳米颗粒（NPs）被使用的几个领域。MONMs可以通过破坏细胞壁来对抗耐抗生素细菌，为目标组织提供受控的药物输送，增强MRI对比以更好地诊断疾病，并直接向肿瘤/癌症提供化疗，最大限度地减少副作用。尽管存在与毒性和稳定性相关的挑战，monm在改善医疗方面使这些NPs成为解决抗生素耐药性等关键问题和提高现代医疗保健诊断和治疗效果的改变游戏规则的解决方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Materials Letters 工程技术-材料科学：综合

CiteScore

5.60

自引率

3.30%

发文量

1948

审稿时长

50 days

期刊介绍： Materials Letters has an open access mirror journal Materials Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Materials Letters is dedicated to publishing novel, cutting edge reports of broad interest to the materials community. The journal provides a forum for materials scientists and engineers, physicists, and chemists to rapidly communicate on the most important topics in the field of materials. Contributions include, but are not limited to, a variety of topics such as: • Materials - Metals and alloys, amorphous solids, ceramics, composites, polymers, semiconductors • Applications - Structural, opto-electronic, magnetic, medical, MEMS, sensors, smart • Characterization - Analytical, microscopy, scanning probes, nanoscopic, optical, electrical, magnetic, acoustic, spectroscopic, diffraction • Novel Materials - Micro and nanostructures (nanowires, nanotubes, nanoparticles), nanocomposites, thin films, superlattices, quantum dots. • Processing - Crystal growth, thin film processing, sol-gel processing, mechanical processing, assembly, nanocrystalline processing. • Properties - Mechanical, magnetic, optical, electrical, ferroelectric, thermal, interfacial, transport, thermodynamic • Synthesis - Quenching, solid state, solidification, solution synthesis, vapor deposition, high pressure, explosive