Influence of Sr and Cu elements on the glass-forming ability and corrosion performance of Ca-based biomedical materials

IF 3.2 3区材料科学 Q1 MATERIALS SCIENCE, CERAMICS

Journal of Non-crystalline Solids Pub Date : 2025-06-14 DOI:10.1016/j.jnoncrysol.2025.123677

Liying Ma , Yue Wang , Lixing Min , Yong Zhang , Guihong Geng

{"title":"Influence of Sr and Cu elements on the glass-forming ability and corrosion performance of Ca-based biomedical materials","authors":"Liying Ma , Yue Wang , Lixing Min , Yong Zhang , Guihong Geng","doi":"10.1016/j.jnoncrysol.2025.123677","DOIUrl":null,"url":null,"abstract":"<div><div>Ca-based bulk metallic glasses (BMGs) have attracted significant attention due to their high strength, low elastic modulus, excellent corrosion resistance, and good biocompatibility. However, their limited glass-forming ability (GFA) and difficulty in precisely controlling the degradation rate restrict their potential for clinical applications. In this study, we investigated the effects of adding different amounts of Sr and Cu on the GFA, corrosion behavior, and cytocompatibility of Ca<sub>63</sub>Mg<sub>20</sub>Zn<sub>17</sub> alloy. The results showed that the addition of Sr decreased the GFA of the alloy but enhanced its corrosion resistance. In contrast, the addition of Cu improved the GFA and corrosion resistance to some extent, but the performance decreased when the Cu content exceeded 1 at. %. Cytotoxicity tests indicated that all the alloys exhibited good biocompatibility and were non-toxic to cells. This study provides a theoretical basis for the application of Ca-based BMGs in biomedical materials and offers scientific support for the development of novel degradable implant materials.</div></div>","PeriodicalId":16461,"journal":{"name":"Journal of Non-crystalline Solids","volume":"666 ","pages":"Article 123677"},"PeriodicalIF":3.2000,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Non-crystalline Solids","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022309325002923","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, CERAMICS","Score":null,"Total":0}

引用次数: 0

Abstract

Ca-based bulk metallic glasses (BMGs) have attracted significant attention due to their high strength, low elastic modulus, excellent corrosion resistance, and good biocompatibility. However, their limited glass-forming ability (GFA) and difficulty in precisely controlling the degradation rate restrict their potential for clinical applications. In this study, we investigated the effects of adding different amounts of Sr and Cu on the GFA, corrosion behavior, and cytocompatibility of Ca₆₃Mg₂₀Zn₁₇ alloy. The results showed that the addition of Sr decreased the GFA of the alloy but enhanced its corrosion resistance. In contrast, the addition of Cu improved the GFA and corrosion resistance to some extent, but the performance decreased when the Cu content exceeded 1 at. %. Cytotoxicity tests indicated that all the alloys exhibited good biocompatibility and were non-toxic to cells. This study provides a theoretical basis for the application of Ca-based BMGs in biomedical materials and offers scientific support for the development of novel degradable implant materials.

查看原文本刊更多论文

Sr和Cu元素对ca基生物医用材料玻璃化能力和腐蚀性能的影响

钙基大块金属玻璃（bmg）因其高强度、低弹性模量、优异的耐腐蚀性和良好的生物相容性而备受关注。然而，它们有限的玻璃形成能力（GFA）和难以精确控制降解速率限制了它们的临床应用潜力。在本研究中，我们研究了添加不同量的Sr和Cu对Ca63Mg20Zn17合金的GFA、腐蚀行为和细胞相容性的影响。结果表明，Sr的加入降低了合金的GFA，但提高了合金的耐蚀性。相比之下，Cu的加入在一定程度上提高了GFA和耐蚀性，但当Cu含量超过1 at时，性能下降。%。细胞毒性试验表明，所有合金均具有良好的生物相容性，对细胞无毒。本研究为ca基bmg在生物医用材料中的应用提供了理论基础，为新型可降解植入材料的开发提供了科学支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Non-crystalline Solids 工程技术-材料科学：硅酸盐

CiteScore

6.50

自引率

11.40%

发文量

576

审稿时长

35 days

期刊介绍： The Journal of Non-Crystalline Solids publishes review articles, research papers, and Letters to the Editor on amorphous and glassy materials, including inorganic, organic, polymeric, hybrid and metallic systems. Papers on partially glassy materials, such as glass-ceramics and glass-matrix composites, and papers involving the liquid state are also included in so far as the properties of the liquid are relevant for the formation of the solid. In all cases the papers must demonstrate both novelty and importance to the field, by way of significant advances in understanding or application of non-crystalline solids; in the case of Letters, a compelling case must also be made for expedited handling.