{"title":"The Detoxifying Effects of <i>Spirulina</i> in Promoting Liver Health and Heavy Metal Elimination - A Review.","authors":"Sunil Namdeo Thitame, Ashwini Ashok Aher, Viddyasagar Mopagar","doi":"10.4103/jpbs.jpbs_570_25","DOIUrl":null,"url":null,"abstract":"<p><p><i>Spirulina</i>, a blue-green algae rich in essential nutrients, has garnered significant attention for its potential health benefits, particularly its role in liver detoxification and the elimination of heavy metals. This review explores the detoxifying effects of <i>spirulina</i>, focusing on its ability to enhance liver health and facilitate the removal of toxic metals from the body. <i>Spirulina</i> contains bioactive compounds such as phycocyanin, chlorophyll, and various antioxidants, which have been shown to possess hepatoprotective properties. Studies highlight <i>spirulina's</i> capacity to reduce oxidative stress, inflammation, and liver enzyme markers associated with liver damage. Furthermore, <i>spirulina's</i> chelating agents support the binding and excretion of heavy metals, such as lead, mercury, and cadmium, from the body. The synergistic effects of <i>spirulina</i> on liver function and detoxification processes present a promising avenue for alternative therapeutic interventions in mitigating the harmful effects of environmental pollutants and supporting liver health. This review synthesizes current research findings, providing an in-depth understanding of the molecular mechanisms through which <i>spirulina</i> may aid in detoxification and liver protection, while also highlighting the need for further clinical studies to validate these therapeutic claims.</p>","PeriodicalId":94339,"journal":{"name":"Journal of pharmacy & bioallied sciences","volume":"17 Suppl 1","pages":"S43-S45"},"PeriodicalIF":0.7000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12156544/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of pharmacy & bioallied sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jpbs.jpbs_570_25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/2 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Spirulina, a blue-green algae rich in essential nutrients, has garnered significant attention for its potential health benefits, particularly its role in liver detoxification and the elimination of heavy metals. This review explores the detoxifying effects of spirulina, focusing on its ability to enhance liver health and facilitate the removal of toxic metals from the body. Spirulina contains bioactive compounds such as phycocyanin, chlorophyll, and various antioxidants, which have been shown to possess hepatoprotective properties. Studies highlight spirulina's capacity to reduce oxidative stress, inflammation, and liver enzyme markers associated with liver damage. Furthermore, spirulina's chelating agents support the binding and excretion of heavy metals, such as lead, mercury, and cadmium, from the body. The synergistic effects of spirulina on liver function and detoxification processes present a promising avenue for alternative therapeutic interventions in mitigating the harmful effects of environmental pollutants and supporting liver health. This review synthesizes current research findings, providing an in-depth understanding of the molecular mechanisms through which spirulina may aid in detoxification and liver protection, while also highlighting the need for further clinical studies to validate these therapeutic claims.