Sweet Shield: Enhancing Oral Health with Bioactive HETAFU Candies in Adults - A Dose-Dependent Study.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2025-05-01 Epub Date: 2025-04-25 DOI:10.4103/jpbs.jpbs_16_25
Sowjanya Lakkoju, Deepika Bolisetty, Ranjith Kumar
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引用次数: 0

Abstract

Functional foods incorporating probiotics, essential oils, and DHA, PhosphatidylSerine have been explored as innovative approaches to improving oral health. This study evaluates the effects of consuming two versus five HETAFU candies daily on oral microbial levels over eight weeks. To compare the impact of moderate (two candies/day) and higher (five candies/day) HETAFU candy consumption on oral microbial populations, focusing on Streptococcus mutans, Lactobacillus, Actinomycetes, and Candida. A total of 200 participants were randomly divided into two groups: Group 1 consumed two candies daily, and Group 2 consumed five candies daily. Microbial levels were measured at baseline, 2 weeks, 4 weeks, and 8 weeks using microbiological techniques. Statistical analysis included Z scores and P values to determine the significance of microbial changes between groups. Both groups showed significant reductions in Streptococcus mutans and Candida, with a concurrent decrease in Lactobacillus and Actinomycetes levels over time. However, Group 2 demonstrated greater microbial shifts, indicating enhanced modulation of the oral microbiome with higher candy consumption. Higher consumption of HETAFU candies (five/day) provides superior benefits in reducing pathogenic microbes and promoting beneficial bacteria compared to moderate consumption (two/day). This suggests a dose-dependent relationship, with increased intake offering additional protective effects against oral microbial imbalances. Functional foods like HETAFU candies represent a promising adjunct to oral hygiene practices.

甜盾:增强口腔健康与成人的生物活性HETAFU糖果-剂量依赖性研究。
含有益生菌、精油、DHA、磷脂酰丝氨酸的功能性食品已被探索作为改善口腔健康的创新方法。这项研究评估了在八周内每天食用两颗和五颗HETAFU糖果对口腔微生物水平的影响。比较中等(2颗糖/天)和较高(5颗糖/天)食用HETAFU糖对口腔微生物种群的影响,重点关注变形链球菌、乳杆菌、放线菌和念珠菌。共有200名参与者被随机分为两组:第一组每天吃两颗糖,第二组每天吃五颗糖。使用微生物学技术在基线、2周、4周和8周测量微生物水平。统计分析采用Z评分和P值来确定组间微生物变化的显著性。随着时间的推移,两组均显示变形链球菌和念珠菌显著减少,乳酸杆菌和放线菌水平同时下降。然而,第二组表现出更大的微生物变化,表明随着糖果摄入量的增加,口腔微生物组的调节增强。食用较多的HETAFU糖果(每天5颗)与适量食用(每天2颗)相比,在减少致病微生物和促进有益细菌方面具有更大的益处。这表明一种剂量依赖关系,增加摄入量对口腔微生物失衡有额外的保护作用。像HETAFU糖果这样的功能性食品代表了一种很有前途的口腔卫生辅助措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.40
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0.00%
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