Prevalence of Vitamin D Deficiency Among Children (0-12 Years) in Secondary Care Hospital: A Cross-Sectional Study Over One Year Period.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2025-05-01 Epub Date: 2025-04-29 DOI:10.4103/jpbs.jpbs_144_25
Yousef Alrohaimi, Badar A Almuqhem
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Abstract

Objective: This study was carried out to assess the prevalence of vitamin D deficiency and insufficiency in study group of children aged 0 to 12 years.

Methods: This cross-sectional study was conducted to identify associations between serum 25-hydroxy vitamin D (25-OHD), calcium, phosphorus, and alkaline phosphatase levels by gender in the study population and to assess the prevalence of vitamin D deficiency and insufficiency in the study group of children aged 0 to 12 years visiting secondary care hospital in 1 year between February 2015 and March 2016 in King Khalid Hospital in Majmaah city. Serum 25-OHD, calcium, and phosphorus concentrations, serum alkaline phosphatase (ALP) levels were measured.

Results: The median (range) concentrations of 25-OHD were 28.83 in males and 27.02 in females (P = 0.65). The prevalence of mild, moderate, and severe vitamin D deficiencies among the study population was 38.7%, 45.3%, and 10.7%, respectively. There was no significant correlation of serum 25-OHD, calcium, phosphorus, and alkaline phosphatase levels was observed with gender in the study population. No gender-based differences were observed in the serum levels of 25-OHD, calcium, phosphorus, or alkaline phosphatase.

Conclusion: Vitamin D deficiency and insufficiency were highly prevalent among children aged 0 to 12 years. No significant gender-based differences were found in vitamin D or related biochemical markers. These results emphasize the importance of routine screening and preventive measures in pediatric care.

二级医院儿童(0-12岁)维生素D缺乏症患病率:一项为期一年的横断面研究
目的:了解0 ~ 12岁儿童维生素D缺乏和不足的患病率。方法:本横断面研究旨在确定研究人群中按性别区分的血清25-羟基维生素D (25-OHD)、钙、磷和碱性磷酸酶水平之间的关系,并评估2015年2月至2016年3月在Majmaah市King Khalid医院1年内到二级保健医院就诊的0至12岁儿童研究组中维生素D缺乏和不足的患病率。测定血清25-OHD、钙、磷浓度及血清碱性磷酸酶(ALP)水平。结果:25-OHD的中位(范围)浓度男性为28.83,女性为27.02 (P = 0.65)。研究人群中轻度、中度和重度维生素D缺乏症的患病率分别为38.7%、45.3%和10.7%。在研究人群中,血清25-OHD、钙、磷和碱性磷酸酶水平与性别无显著相关性。血清25-OHD、钙、磷或碱性磷酸酶水平无性别差异。结论:维生素D缺乏和不足在0 ~ 12岁儿童中普遍存在。在维生素D或相关生化指标上没有发现明显的性别差异。这些结果强调了常规筛查和预防措施在儿科护理中的重要性。
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CiteScore
1.40
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