Incidence Progression and Epidemiological Study of Oral Precancerous Lesions: An Original Research.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2025-05-01 Epub Date: 2025-02-25 DOI:10.4103/jpbs.jpbs_1419_24
Monalisha Mahapatra, Kaushal P Tripathi, Trapti S Bhadouria, Sathvik Rai, Aakash Malik, Sanchitha Murali, Heena D Tiwari
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引用次数: 0

Abstract

Introduction: Oral precancerous lesions, such as leukoplakia and erythroplakia, are significant contributors to the global burden of oral cancer. Understanding their epidemiology, incidence, and progression is essential to early detection and prevention. In India, these lesions are prevalent due to widespread tobacco consumption and other lifestyle factors, leading to an increased risk of oral cancer development.

Methods: A prospective observational study was conducted with 150 patients showing clinical signs of oral precancerous lesions. Three parameters were analyzed: patient demographics, lesion characteristics, and risk factor associations. Incidence and progression data were statistically analyzed using appropriate tests.

Results: Our study identified key demographic groups at higher risk, with significant lesion progression in specific subpopulations. Statistical analysis showed strong associations between tobacco use and lesion development, consistent with previous studies.

Conclusion: This study highlights the incidence and progression of oral precancerous lesions and their significant correlation with risk factors, emphasizing the need for early intervention strategies.

口腔癌前病变的发病率、进展和流行病学研究:一项原始研究。
口腔癌前病变,如白斑和红斑,是全球口腔癌负担的重要贡献者。了解其流行病学、发病率和进展对早期发现和预防至关重要。在印度,由于广泛的烟草消费和其他生活方式因素,这些病变很普遍,导致口腔癌发展的风险增加。方法:对150例有口腔癌前病变临床症状的患者进行前瞻性观察研究。分析了三个参数:患者人口统计学、病变特征和危险因素关联。采用适当的试验对发病率和进展数据进行统计分析。结果:我们的研究确定了高危人群,在特定亚群中有显著的病变进展。统计分析显示,烟草使用与病变发展之间存在很强的关联,这与以前的研究结果一致。结论:本研究强调了口腔癌前病变的发生率和进展及其与危险因素的显著相关性,强调了早期干预策略的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
1.40
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0.00%
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