Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2025-05-01 Epub Date: 2025-02-25 DOI:10.4103/jpbs.jpbs_1441_24
Neha Khaire, Janvi B Movva, Vishwa Desai, Divya S Gunnam, Prashant A Karni, Ayushi Patel, Afroz Kalmee Syed
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引用次数: 0

Abstract

Introduction: Oral premalignant lesions (OPLs) are precursors to oral cancer and are commonly associated with lifestyle risk factors, particularly tobacco and alcohol use. Identifying the prevalence and associated risk factors of OPLs in a tertiary care setting is crucial for developing targeted interventions.

Methods: This cross-sectional study was conducted among patients presenting to a tertiary care hospital. The prevalence of OPLs was assessed, and risk factors such as tobacco use, alcohol consumption, and betel quid chewing were evaluated. Statistical analysis was conducted to determine significant associations between risk factors and the presence of OPLs.

Results: The prevalence of OPLs was found to be 7.2%, with the highest incidence among individuals with tobacco and quid-chewing habits. Statistical analysis revealed a significant association between tobacco use and the development of OPLs (P < 0.05).

Conclusion: The study highlights the high prevalence of OPLs and their strong association with tobacco and quid-chewing habits. These findings emphasize the need for public health interventions targeting high-risk populations to prevent the progression of OPLs to oral cancer.

某三级医院口腔癌前病变流行病学调查及危险因素分析
口腔癌前病变(opl)是口腔癌的前兆,通常与生活方式风险因素有关,特别是吸烟和饮酒。确定三级医疗机构中开放性开放性疾病的流行情况和相关风险因素对于制定有针对性的干预措施至关重要。方法:本横断面研究在三级保健医院就诊的患者中进行。评估了opl的患病率,并评估了吸烟、饮酒和咀嚼槟榔液等危险因素。进行统计分析以确定危险因素与opl存在之间的显著关联。结果:口腔外伤性溃疡患病率为7.2%,以吸烟、咀嚼液体饮料人群发病率最高。统计分析显示烟草使用与opl的发生有显著相关性(P < 0.05)。结论:该研究强调了口腔外出血的高患病率及其与烟草和咀嚼液体的习惯密切相关。这些发现强调有必要针对高危人群采取公共卫生干预措施,以防止口腔肿瘤发展为口腔癌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
1.40
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