Correlation of Vitamin D in Different Stages of Hypertension as Per JNC 8 Criteria.

Abstract

Background: Recent research over the past few decades has highlighted a link between vitamin D levels and cardiovascular risk factors, particularly blood pressure. The current investigation sought to assess whether serum vitamin D levels are related to blood pressure within Indian population.

Methods: This observational cross-sectional study included 600 participants (300 cases with hypertension and 300 controls). Inclusion criteria were patients aged 20-70 years with hypertension, while individuals with secondary hypertension, chronic kidney disease, or chronic liver disease were excluded. Blood pressure was measured using a mercury sphygmomanometer. Vitamin D levels were analyzed using automated analyzers.

Results: A weak but statistically significant negative association between serum vitamin D levels and blood pressure was found.

Conclusion: Lower serum vitamin D levels were associated with higher systolic blood pressure. It can be suggested that vitamin D exerts an influence on blood pressure, supporting the hypothesis of VDR hypersensitivity.