Evaluation of screw pull-out from plate fixation of en bloc distal radius resection with ulnar reconstruction: Finite element analysis and comparison with experiments on Thiel cadavers.

IF 6.6 3区 医学 Q1 ENGINEERING, BIOMEDICAL
APL Bioengineering Pub Date : 2025-06-11 eCollection Date: 2025-06-01 DOI:10.1063/5.0248553
Wares Chancharoen, Theingi Nwe, Saran Seehanam, Napawan Taradolpisut, Thewarid Berkband, Thanapon Chobpenthai, Chavin Jongwannasiri, Laphatrada Yurasakpong
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Abstract

Fractures of the distal radius often require surgical intervention, with plate fixation being a standard stabilization method. Screw loosening and pull-out propose significant complications, necessitating comprehensive understanding of fixation stability factors. This study introduces a novel approach by the combination of finite element analysis (FEA) and experimental investigations on Thiel cadavers to evaluate screw pull-out behavior from plate fixation in en bloc distal radius resection with ulnar reconstruction. In comparison with previous investigations that used computational modeling or fresh-frozen cadaveric specimens, in the present research, FEA predictions specifically experimentally confirm the usage of Thiel cadavers, which better preserve soft tissue elasticity and hydration, thus more closely reflect in vivo conditions. Experimental set-up consisted of bending tests on cadavers and screw pull-out tests in Thiel-cadaveric radius specimens mimicking physiological conditions that induce the effects of screw pull-out. Finite element analysis and simulation were conducted using realistic clinical cases. Biomechanical test results indicated locking-plate deformation and screw loosening, particularly at locations closest to the ulnar bone gap. Torque measurements established various degrees of screw loosening, with the screws closest to the bone gap indicating maximum loosening. FEA demonstrated critical distributions of stresses in screws and locking plates, with good correlations to experimental findings. Screw pull-out force analysis showed vulnerability to loosening, particularly in the area of bone gaps, with findings consistent between biomechanical testing and FEA. This study offers valuable information on the surgical implications and biomechanical considerations of plate fixation for en bloc distal radius resection with ulnar reconstruction.

尺骨重建整块桡骨远端切除钢板内固定螺钉拔出的评价:有限元分析及与Thiel尸体的实验比较。
桡骨远端骨折通常需要手术干预,钢板固定是一种标准的稳定方法。螺钉松动和拔出会引起严重的并发症,需要全面了解固定稳定性因素。本研究采用有限元分析(FEA)和Thiel尸体实验研究相结合的新方法来评估桡骨远端整体切除尺骨重建钢板固定后螺钉拔出行为。与以往使用计算模型或新鲜冷冻尸体标本的研究相比,在本研究中,FEA预测专门通过实验证实了Thiel尸体的使用,它更好地保留了软组织的弹性和水合性,从而更接近地反映了体内情况。实验设置包括尸体弯曲试验和thiel -尸体桡骨标本上的螺钉拔出试验,模拟诱发螺钉拔出效应的生理条件。结合实际临床病例进行有限元分析和仿真。生物力学测试结果显示锁定板变形和螺钉松动,特别是在最接近尺骨间隙的位置。扭矩测量确定了不同程度的螺钉松动,最靠近骨间隙的螺钉表示最大程度的松动。有限元分析证明了螺钉和锁紧板的临界应力分布,与实验结果有很好的相关性。螺钉拔出力分析显示易松动,特别是在骨间隙区域,生物力学测试和有限元分析结果一致。本研究为整块桡骨远端切除尺骨重建钢板固定的手术意义和生物力学考虑提供了有价值的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
APL Bioengineering
APL Bioengineering ENGINEERING, BIOMEDICAL-
CiteScore
9.30
自引率
6.70%
发文量
39
审稿时长
19 weeks
期刊介绍: APL Bioengineering is devoted to research at the intersection of biology, physics, and engineering. The journal publishes high-impact manuscripts specific to the understanding and advancement of physics and engineering of biological systems. APL Bioengineering is the new home for the bioengineering and biomedical research communities. APL Bioengineering publishes original research articles, reviews, and perspectives. Topical coverage includes: -Biofabrication and Bioprinting -Biomedical Materials, Sensors, and Imaging -Engineered Living Systems -Cell and Tissue Engineering -Regenerative Medicine -Molecular, Cell, and Tissue Biomechanics -Systems Biology and Computational Biology
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