Breakthrough Infection and Death after COVID-19 Vaccination: A Physics Perspective.

Q3 Medicine
Seyed Ali Reza Mortazavi, Abdollah Jafarzadeh, Abdolkarim Ghadimi-Moghadam, Seyed Mohammad Javad Mortazavi, Masoud Haghani, Ali Ghadimi-Moghadam, Lembit Sihver
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引用次数: 0

Abstract

The largest universal immunization in history has occurred as a result of the COVID-19 pandemic. The developed COVID-19 vaccines have been shown to provide protection against severe forms of COVID-19 by inducing anti-spike neutralizing antibodies. It has been found that individuals who have not been vaccinated against COVID-19 were more likely to contract the virus during a period when the Delta variant was dominant, as compared to those who have received the complete dose of the vaccine, irrespective of the variant. However, there is no notable disparity in the likelihood of hospitalization, requirement for mechanical ventilation, or mortality between the two groups once infected. Nevertheless, those who are unvaccinated may require additional oxygen support. There are reports indicating unfavorable health effects, ranging from transient thyroid dysfunction to death following vaccination. In addition, some people are susceptible to SARS-CoV-2 infection despite they have immunized with the COVID-19 vaccine. Given all these considerations, several key factors should be better understood and considered to enable us to even more successfully manage future pandemics breakthrough infections. The effectiveness of physical treatment methods, e.g., Low Dose Radiation Therapy (LDRT) should be compared to pharmacological treatments.

突破COVID-19疫苗接种后的感染和死亡:物理学视角。
由于COVID-19大流行,历史上最大规模的普遍免疫接种发生了。已开发的COVID-19疫苗已被证明通过诱导抗刺突中和抗体来提供对严重形式的COVID-19的保护。研究发现,与接种了完整剂量疫苗的人相比,未接种COVID-19疫苗的人在Delta变体占主导地位的时期更有可能感染病毒,而不管变体是什么。然而,两组在感染后住院的可能性、机械通气需求或死亡率方面没有显着差异。然而,那些未接种疫苗的人可能需要额外的氧气支持。有报告指出对健康不利的影响,从短暂的甲状腺功能障碍到接种后死亡。此外,有些人尽管接种了COVID-19疫苗,但仍容易感染SARS-CoV-2。考虑到所有这些因素,应该更好地了解和考虑几个关键因素,使我们能够更成功地管理未来的大流行突破性感染。物理治疗方法,如低剂量放射治疗(LDRT)的有效性应与药物治疗进行比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Biomedical Physics and Engineering
Journal of Biomedical Physics and Engineering Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
2.90
自引率
0.00%
发文量
64
审稿时长
10 weeks
期刊介绍: The Journal of Biomedical Physics and Engineering (JBPE) is a bimonthly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research (experimental or theoretical) broadly concerned with the relationship of physics to medicine and engineering.
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