Ángel M Ortiz-Zúñiga, Olga Simó-Servat, Jordi Samaniego, Fátima Cuadra-Espinilla, Mónica Sánchez, Rafael Simó, Cristina Hernández
{"title":"Time in Range Is Closely Related to Healing Time of Diabetic Foot Ulcers.","authors":"Ángel M Ortiz-Zúñiga, Olga Simó-Servat, Jordi Samaniego, Fátima Cuadra-Espinilla, Mónica Sánchez, Rafael Simó, Cristina Hernández","doi":"10.1111/wrr.70052","DOIUrl":null,"url":null,"abstract":"<p><p>Diabetic foot ulcer is a meaningful risk factor for limb amputation. The aim of this study was to evaluate the relationship between parameters provided by Continuous Glucose Monitoring and the healing time of DFUs in the real world. This pilot prospective study included patients with Type 2 diabetes with DFUs grade I-II (stage A-C) of the University of Texas Diabetic Wound Classification System, treated in an outpatient Diabetic Foot Unit according to standards of care. Participants were fitted with a CGM device until the ulcer closure. We observed an inverse correlation between the elapsed time to achieve a complete ulcer closure and Time in Range (p = 0.005). In addition, a direct correlation was found between the time required for ulcer healing and both Time Above Range and Glucose Management Indicator (p < 0.05). Glycaemic control is directly related to ulcer wound healing in non-complicated diabetic foot ulcer.</p>","PeriodicalId":23864,"journal":{"name":"Wound Repair and Regeneration","volume":"33 3","pages":"e70052"},"PeriodicalIF":3.4000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wound Repair and Regeneration","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/wrr.70052","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Diabetic foot ulcer is a meaningful risk factor for limb amputation. The aim of this study was to evaluate the relationship between parameters provided by Continuous Glucose Monitoring and the healing time of DFUs in the real world. This pilot prospective study included patients with Type 2 diabetes with DFUs grade I-II (stage A-C) of the University of Texas Diabetic Wound Classification System, treated in an outpatient Diabetic Foot Unit according to standards of care. Participants were fitted with a CGM device until the ulcer closure. We observed an inverse correlation between the elapsed time to achieve a complete ulcer closure and Time in Range (p = 0.005). In addition, a direct correlation was found between the time required for ulcer healing and both Time Above Range and Glucose Management Indicator (p < 0.05). Glycaemic control is directly related to ulcer wound healing in non-complicated diabetic foot ulcer.
期刊介绍：
Wound Repair and Regeneration provides extensive international coverage of cellular and molecular biology, connective tissue, and biological mediator studies in the field of tissue repair and regeneration and serves a diverse audience of surgeons, plastic surgeons, dermatologists, biochemists, cell biologists, and others.
Wound Repair and Regeneration is the official journal of The Wound Healing Society, The European Tissue Repair Society, The Japanese Society for Wound Healing, and The Australian Wound Management Association.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
