Juan Carlos Lona-Reyes, Lucia Miramontes-Buiza, Luis Fernando Frías-Flores, Jose Angel Regla-Nava, Jesús González-Carmona, Juan Antonio Gallegos-Marín, Mariana Chávez-Rodríguez
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引用次数: 0
Abstract
This study aimed to identify factors associated with neonatal sepsis due to Serratia marcescens in a Neonatal Intensive Care Unit (NICU) in Mexico. A case-control study was conducted, matched by gestational age and birth weight. The analysis was performed using logistic regression. Seventy newborns with S. marcescens sepsis were identified; the median gestational age was 34.4 weeks, and the median birth weight was 1680g. Microbial isolates were identified in the bloodstream in 98.6% of cases, and 88.6% of these were diagnosed after 72h of life. Independent variables associated with infection were the presence of a central venous catheter (OR 5.17; 95% CI 1.57-17.1), mechanical ventilation (OR 3.23; 95% CI 1.18-8.87), and prior use of meropenem (OR 3.38; 95% CI 1.01-11.3). The case fatality rate of the infection was 32.9%.
本研究旨在确定与墨西哥新生儿重症监护病房（NICU）中粘质沙雷菌引起的新生儿败血症相关的因素。进行了一项病例对照研究，与胎龄和出生体重相匹配。采用逻辑回归进行分析。70例新生儿肉质葡萄球菌脓毒症；中位胎龄为34.4周，中位出生体重为1680g。98.6%的病例在血液中发现了分离的微生物，其中88.6%在生命72小时后被诊断出来。与感染相关的独立变量是中心静脉导管的存在(OR 5.17；95% CI 1.57-17.1)，机械通气(OR 3.23；95% CI 1.18-8.87)，既往使用美罗培南(OR 3.38；95% ci 1.01-11.3)。感染病死率为32.9%。
期刊介绍：
La Revista Argentina de Microbiología es una publicación trimestral editada por la Asociación Argentina de Microbiología y destinada a la difusión de trabajos científicos en las distintas áreas de la Microbiología. La Asociación Argentina de Microbiología se reserva los derechos de propiedad y reproducción del material aceptado y publicado.
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