Convergent validity, reliability and responsiveness of the AP-7D and EQ-5D-5L based on the survey for the general people in five countries: a new cultural-specific preference-based measure developed in east and southeast asia.
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Abstract
Background: The AP-7D is a preference-based measure that was recently developed for use in East and Southeast Asia. This study investigated the reliability and convergent validity of the new instrument.
Methods: For this, surveys were conducted in Japan, Korea, China, Thailand, and Singapore. In each country, 500 respondents were selected using quota sampling and were stratified by sex and age. We conducted a face-to-face survey in Japan and a web-based survey in the remaining countries at two time points. The AP-7D and the EQ-5D-5L were collected from all countries, and the SF-6D was only collected in Japan. The instruments' reliabilities were confirmed by comparing the responses using self-report test-retest methods. For convergent validity, we compared responses provided to the AP-7D with those provided to the EQ-5D-5L and the SF-6D based on predetermined hypotheses.
Results: The percentage of agreement between the two surveys (in separate categories) was 73.9% (pain/discomfort), 71.2% (mental health), 68.6% (energy), 89.6% (mobility), 82.1% (work/school), 84.3% (social relations), and 86.4% (burden to others) in the five countries. These values demonstrate equivalent performance to those of the EQ-5D-5L. The kappa coefficients for the AP-7D items were similar to those for the EQ-5D-5L. In the correlation matrix between the AP-7D and EQ-5D-5L, correlation exceeded 0.5 in the following items: 0.69 between "mental health" (AP-7D) and "anxiety/depression" (EQ-5D-5L), 0.54 for "pain/discomfort" in both, 0.51 between "energy" (AP-7D) and "anxiety/depression" (EQ-5D-5L), and 0.50 for "mobility" in both.
Conclusions: The results of this survey showed the good test-retest reliability and convergent validity of the AP-7D. The basic psychometric properties of the new instrument were confirmed.
期刊介绍：
Health and Quality of Life Outcomes is an open access, peer-reviewed, journal offering high quality articles, rapid publication and wide diffusion in the public domain.
Health and Quality of Life Outcomes considers original manuscripts on the Health-Related Quality of Life (HRQOL) assessment for evaluation of medical and psychosocial interventions. It also considers approaches and studies on psychometric properties of HRQOL and patient reported outcome measures, including cultural validation of instruments if they provide information about the impact of interventions. The journal publishes study protocols and reviews summarising the present state of knowledge concerning a particular aspect of HRQOL and patient reported outcome measures. Reviews should generally follow systematic review methodology. Comments on articles and letters to the editor are welcome.
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