Suspected clinical methemoglobinemia associated with administration of hydrogen peroxide 3% in a dog treated for acute ibuprofen ingestion.

IF 0.9 4区农林科学 Q3 VETERINARY SCIENCES

Canadian Veterinary Journal-revue Veterinaire Canadienne Pub Date : 2025-06-01

Dominique Dominguez, Rebecca Walton

引用次数: 0

Abstract

An 8-month-old intact male golden retriever dog was presented to the emergency department of a large private-practice specialty hospital. The dog had become cyanotic and collapsed following administration (orogastric tube) of 1.4 mL/kg of hydrogen peroxide 3% to induce emesis for ibuprofen ingestion. The dog had severe methemoglobinemia (33%; reference range: 0.3 to 1.5%) and developed anemia. The methemoglobinemia resolved after 24 h of hospitalization with supportive care. Results from assessment with high-performance liquid chromatography/tandem mass spectrometry were consistent with ibuprofen ingestion, with no acetaminophen detected. Key clinical message: This case demonstrated methemoglobinemia in a dog following both ibuprofen ingestion and hydrogen peroxide 3% administration.

本刊更多论文

疑似临床高铁血红蛋白血症与服用3%过氧化氢治疗急性布洛芬的狗。

一只8个月大的完整雄性金毛猎犬被送到一家大型私人专业医院的急诊科。经胃管注入1.4 mL/kg 3%过氧化氢诱导布洛芬呕吐后，犬变紫并晕倒。狗有严重的高铁血红蛋白血症(33%；参考范围：0.3 - 1.5%)并发展为贫血。高铁血红蛋白血症在支持治疗下住院24小时后消退。高效液相色谱/串联质谱分析结果与摄入布洛芬一致，未检出对乙酰氨基酚。关键临床信息：本病例显示狗在摄入布洛芬和3%过氧化氢后出现高铁血红蛋白血症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Canadian Veterinary Journal-revue Veterinaire Canadienne 农林科学-兽医学

CiteScore

1.20

自引率

10.00%

发文量

177

审稿时长

12-24 weeks

期刊介绍： The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health. A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).