A novel fem framework for correlative study of mechanical properties of normal and osteoporotic human bone.

Abstract

BackgroundOsteoporosis is a prevalent bone disease which results in increased bone porosity and decreased bone density, which in turn raises the risk of fractures. A conflict between bone formation (the process of creating new bone tissue) and bone resorption (the degradation and removal of old bone tissue) causes the disorder. This imbalance causes the process of bone remodelling to be disrupted, which weakens the bone structures.ObjectiveDue to intrinsic anatomical differences, previous research on the prediction of bone failure has been imprecise. It requires improvement for load scenarios and validation for various demographics, ultimately leading to low accuracy.MethodsTo overcome these limitations, this study proposes a novel Finite Element analysis framework for predicting osteoporosis with the mechanical properties of human bone for stress, strain estimation.ResultsAs a result of this proposed framework proves its significance with stress in healthy bones is 2.557541680090727e-04 and bones with osteoporosis is 1.814480251460656e-03, young's modulus of healthy bones and unhealthy bones are 7.019135266051970e + 10 and 0.6158529354739577e + 10, the von Mises stress for healthy bone is 2.4897e + 07, and for the unhealthy bone is 2.8638e + 07, finally, the maximum deflection in healthy bone is 1.0235e-03, for unhealthy bone is 2.1182e-03.ConclusionThus the proposed model provides significant results in the presence or absence of osteoporosis disease.