Le Zhong, Yunqian Sun, Yunhao Sun, Guohui Yu, Ping Cheng, Jinshui Zheng, Donghai Peng, Ming Sun
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引用次数: 0
Abstract
Klebsiella variicola, an emerging pathogen, significantly impacts banana production by causing bacterial sheath rot. Research has shown that phages are effective in treating bacterial infections. In this study, two lytic K. variicola bacteriophages, PZK-KV7 and PZK-KV23, were isolated from a banana plantation area in Guangdong Province, their biological characteristics were examined, and their whole genomes were sequenced. Both phages were found to belong to the genus Sugarlandvirus of the family Demerecviridae. No antibiotic resistance or virulence genes were identified in either of these phages. One-step growth curve analysis revealed that phages PZK-KV7 and PZK-KV23 have a short latency time and a large burst size. pH tolerance tests revealed that both phages remain stable over a broad pH range (pH 4-12). The ability of these phages to inhibit the growth of K. variicola indicates their potential utility for managing K. variicola infections in banana cultivation.
期刊介绍：
Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.
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