Multi-residue environmental method for seed treatment insecticides, neonicotinoid degradation products, and fungicides using liquid chromatography tandem mass spectrometry with a new ionization source.

IF 3.8 2区化学 Q1 BIOCHEMICAL RESEARCH METHODS

Analytical and Bioanalytical Chemistry Pub Date : 2025-06-13 DOI:10.1007/s00216-025-05927-8

Jascika A A Maclean, Shannon Bartelt-Hunt, Joyce Cristale, Sathaporn Onanong, Daniel D Snow

{"title":"Multi-residue environmental method for seed treatment insecticides, neonicotinoid degradation products, and fungicides using liquid chromatography tandem mass spectrometry with a new ionization source.","authors":"Jascika A A Maclean, Shannon Bartelt-Hunt, Joyce Cristale, Sathaporn Onanong, Daniel D Snow","doi":"10.1007/s00216-025-05927-8","DOIUrl":null,"url":null,"abstract":"<p><p>Few methods provide simultaneous determination of multiple pesticides and degradation products in environmental samples using liquid chromatography tandem mass spectrometry (LC-MS/MS). As LC-MS/MS method performance is significantly influenced by the type and design of the ion source, we compared three ion sources: electrospray ionization (ESI) source, atmospheric pressure chemical ionization (APCI) source and UniSpray™ ionization source. A gain in sensitivity was observed with UniSpray™ and ESI as compared to APCI source on the same instrument. Matrix effects in the three interfaces were evaluated in reagent water and wastewater extracts. UniSpray™ showed the lowest matrix effect among the three sources, with APCI exhibiting more pronounced signal enhancement. A solid-phase extraction method using the UniSpray™ source provides method detection limits (MDLs) ranging from 0.00189 to 0.0209 µg/L in extracts from water samples. Recoveries in water ranged up to 94.35%, with above 60% of the pesticides having an average recovery exceeding 70%.</p>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical and Bioanalytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s00216-025-05927-8","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}

引用次数: 0

Abstract

Few methods provide simultaneous determination of multiple pesticides and degradation products in environmental samples using liquid chromatography tandem mass spectrometry (LC-MS/MS). As LC-MS/MS method performance is significantly influenced by the type and design of the ion source, we compared three ion sources: electrospray ionization (ESI) source, atmospheric pressure chemical ionization (APCI) source and UniSpray™ ionization source. A gain in sensitivity was observed with UniSpray™ and ESI as compared to APCI source on the same instrument. Matrix effects in the three interfaces were evaluated in reagent water and wastewater extracts. UniSpray™ showed the lowest matrix effect among the three sources, with APCI exhibiting more pronounced signal enhancement. A solid-phase extraction method using the UniSpray™ source provides method detection limits (MDLs) ranging from 0.00189 to 0.0209 µg/L in extracts from water samples. Recoveries in water ranged up to 94.35%, with above 60% of the pesticides having an average recovery exceeding 70%.

查看原文本刊更多论文

新型电离源液相色谱串联质谱法用于种子处理杀虫剂、新烟碱类降解产物和杀菌剂的多残留环境分析。

液相色谱串联质谱法（LC-MS/MS）能同时测定环境样品中多种农药和降解产物的方法很少。由于LC-MS/MS方法的性能受到离子源类型和设计的显著影响，我们比较了三种离子源：电喷雾电离（ESI）源、大气压化学电离（APCI）源和UniSpray™电离源。与同一仪器上的APCI源相比，UniSpray™和ESI的灵敏度有所提高。在试剂水和废水萃取液中评价了三种界面的基质效应。在三个源中，UniSpray™显示出最低的矩阵效应，APCI显示出更明显的信号增强。使用UniSpray™源的固相萃取方法在水样提取物中提供方法检测限（mdl）范围为0.00189至0.0209 μ g/L。在水中的回收率可达94.35%，60%以上的农药平均回收率超过70%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Analytical and Bioanalytical Chemistry 化学-分析化学

CiteScore

8.00

自引率

4.70%

发文量

638

审稿时长

2.1 months

期刊介绍： Analytical and Bioanalytical Chemistry’s mission is the rapid publication of excellent and high-impact research articles on fundamental and applied topics of analytical and bioanalytical measurement science. Its scope is broad, and ranges from novel measurement platforms and their characterization to multidisciplinary approaches that effectively address important scientific problems. The Editors encourage submissions presenting innovative analytical research in concept, instrumentation, methods, and/or applications, including: mass spectrometry, spectroscopy, and electroanalysis; advanced separations; analytical strategies in “-omics” and imaging, bioanalysis, and sampling; miniaturized devices, medical diagnostics, sensors; analytical characterization of nano- and biomaterials; chemometrics and advanced data analysis.