{"title":"Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients.","authors":"Haojie Li, Xinyu Lin, Xinglu Li, Nan Chen, Xie Wu","doi":"10.1016/j.isci.2025.112682","DOIUrl":null,"url":null,"abstract":"<p><p>Hypertension adversely affects glycolipid metabolism and vascular function in aging populations. This network meta-analysis evaluated 36 randomized trials (<i>n</i> = 2875) comparing traditional mind-body exercises (Tai Chi, Baduanjin, Daoyinyangshengshu) for metabolic and vascular improvements. Analyses revealed Tai Chi most effectively raised high-density lipoprotein (HDL) (standardized mean differences [SMD] = 0.88), while Daoyinyangshengshu optimally reduced fasting glucose (SMD = -1.21) and endothelin-1 (SMD = -1.82) while increasing nitric oxide (SMD = 1.41). Baduanjin best lowered low-density lipoprotein (LDL) (SMD = -0.95), with other exercises improving cholesterol and triglycerides. The findings demonstrate that specific mind-body practices differentially enhance cardiometabolic health, with Tai Chi and Daoyinyangshengshu showing particular promise for comprehensive benefits. These evidence-based results support incorporating traditional exercises into hypertension management protocols to address both metabolic and vascular dysfunction.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 6","pages":"112682"},"PeriodicalIF":4.1000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12159935/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"iScience","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1016/j.isci.2025.112682","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/20 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Hypertension adversely affects glycolipid metabolism and vascular function in aging populations. This network meta-analysis evaluated 36 randomized trials (n = 2875) comparing traditional mind-body exercises (Tai Chi, Baduanjin, Daoyinyangshengshu) for metabolic and vascular improvements. Analyses revealed Tai Chi most effectively raised high-density lipoprotein (HDL) (standardized mean differences [SMD] = 0.88), while Daoyinyangshengshu optimally reduced fasting glucose (SMD = -1.21) and endothelin-1 (SMD = -1.82) while increasing nitric oxide (SMD = 1.41). Baduanjin best lowered low-density lipoprotein (LDL) (SMD = -0.95), with other exercises improving cholesterol and triglycerides. The findings demonstrate that specific mind-body practices differentially enhance cardiometabolic health, with Tai Chi and Daoyinyangshengshu showing particular promise for comprehensive benefits. These evidence-based results support incorporating traditional exercises into hypertension management protocols to address both metabolic and vascular dysfunction.
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