{"title":"Pilot study on indirect magnetic resonance lymphography using gadoxetate disodium in dogs.","authors":"Eiichi Kanai, Motohiro Yoshinari, Kouki Yoshikawa, Kazutaka Yamada","doi":"10.1292/jvms.25-0166","DOIUrl":null,"url":null,"abstract":"<p><p>The contrast enhancement between gadoxetate disodium (Gd-EOB-DTPA) and gadodiamide hydrate (Gd-DTPA-BMA) in indirect magnetic resonance lymphography was compared among six healthy beagles. Contrast mediums (0.5 mmol) were injected subcutaneously into the lateral malleolus of the right fibula. Magnetic resonance imaging was performed at 5, 10, 15, 30, 45, and 60 min. The popliteal and medial iliac lymph nodes (LNs) were visualized. Gd-EOB-DTPA had a significantly superior contrast enhancement ratio than Gd-DTPA-BMA at 10 and 15 min at the popliteal LNs. Moreover, Gd-EOB-DTPA had a longer duration of contrast enhancement than Gd-DTPA-BMA in both the popliteal and medial iliac LNs. Gd-EOB-DTPA demonstrated stronger and longer-lasting lymph node enhancement than Gd-DTPA-BMA, thereby indicating its potential application in MR lymphography.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"898-901"},"PeriodicalIF":1.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12344313/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Medical Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1292/jvms.25-0166","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/10 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The contrast enhancement between gadoxetate disodium (Gd-EOB-DTPA) and gadodiamide hydrate (Gd-DTPA-BMA) in indirect magnetic resonance lymphography was compared among six healthy beagles. Contrast mediums (0.5 mmol) were injected subcutaneously into the lateral malleolus of the right fibula. Magnetic resonance imaging was performed at 5, 10, 15, 30, 45, and 60 min. The popliteal and medial iliac lymph nodes (LNs) were visualized. Gd-EOB-DTPA had a significantly superior contrast enhancement ratio than Gd-DTPA-BMA at 10 and 15 min at the popliteal LNs. Moreover, Gd-EOB-DTPA had a longer duration of contrast enhancement than Gd-DTPA-BMA in both the popliteal and medial iliac LNs. Gd-EOB-DTPA demonstrated stronger and longer-lasting lymph node enhancement than Gd-DTPA-BMA, thereby indicating its potential application in MR lymphography.
期刊介绍：
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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