Prevalence and Independent Risk Factors of Anxiety and Depression Symptoms in Glioma Patients: A Cross-Sectional Analysis.

IF 0.5 4区医学 Q4 PHARMACOLOGY & PHARMACY

Psychiatry and Clinical Psychopharmacology Pub Date : 2025-04-18 eCollection Date: 2025-06-01 DOI:10.5152/pcp.2025.241021

Xingyun Zheng, Weizhen Zhang, Yinyou Li, Xiancong Lai, Qingqing Fan, Yueling Xu, Xilong Yin

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Abstract

Background: To investigate the current status of anxiety and depression symptoms in patients with brain glioma and identify the risk factors associated with anxiety and depression symptoms.

Methods: A total of 105 patients diagnosed with glioma at Longgang Central Hospital of Shenzhen from January 2021 to April 2024 were included in this study. The Hospital Anxiety and Depression Scale (HADS) was used to assess the anxiety and depression symptoms of the patients, who were then grouped based on their scores. Chi-square tests and binary logistic regression analyses were performed to identify the independent risk factors for anxiety and depression symptoms in glioma patients.

Results: The average HADS-Anxiety score among glioma patients was 8.72 ± 3.41, with an anxiety symptoms prevalence of 61.90% (65/105). The average HADS-Depression score was 7.73 ± 2.91, with a depression symptoms prevalence of 55.24% (58/105). Among them, 58 patients (55.24%) had both anxiety and depression symptoms, seven patients (6.67%) had only anxiety symptoms, and 40 patients (38.10%) had neither anxiety nor depression. The results of binary tic regression analysis showed that family monthly income, seizures, sleep quality, and cognitive function impairment were independent risk factors for anxiety and depression symptoms (P < .05). Marital status was an independent risk factor for depression symptoms (P < .05).

Conclusion: Glioma patients exhibit a high incidence of anxiety and depression symptoms. The occurrence of these conditions is significantly associated with lower monthly household income, seizure occurrence, sleep disturbances, and cognitive impairment.

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神经胶质瘤患者焦虑和抑郁症状的患病率及独立危险因素：一项横断面分析

背景：探讨脑胶质瘤患者焦虑、抑郁症状的现状，明确与焦虑、抑郁症状相关的危险因素。方法：选取深圳市龙岗区中心医院2021年1月至2024年4月诊断为胶质瘤的患者105例。使用医院焦虑抑郁量表（HADS）评估患者的焦虑和抑郁症状，然后根据他们的得分进行分组。采用卡方检验和二元logistic回归分析确定胶质瘤患者焦虑和抑郁症状的独立危险因素。结果：胶质瘤患者的平均HADS-Anxiety评分为8.72±3.41，焦虑症状患病率为61.90%（65/105）。平均hads -抑郁评分为7.73±2.91，抑郁症状患病率为55.24%（58/105）。其中，58例（55.24%）患者同时有焦虑和抑郁症状，7例（6.67%）患者仅有焦虑症状，40例（38.10%）患者无焦虑和抑郁症状。二元抽动回归分析结果显示，家庭月收入、癫痫发作、睡眠质量和认知功能障碍是焦虑和抑郁症状的独立危险因素（P < 0.05）。婚姻状况是抑郁症状的独立危险因素（P < 0.05）。结论：胶质瘤患者焦虑、抑郁症状发生率高。这些疾病的发生与较低的家庭月收入、癫痫发作、睡眠障碍和认知障碍显著相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychiatry and Clinical Psychopharmacology Medicine-Psychiatry and Mental Health

CiteScore

1.00

自引率

14.30%

发文量

期刊介绍： Psychiatry and Clinical Psychopharmacology aims to reach a national and international audience and will accept submissions from authors worldwide. It gives high priority to original studies of interest to clinicians and scientists in applied and basic neurosciences and related disciplines. Psychiatry and Clinical Psychopharmacology publishes high quality research targeted to specialists, residents and scientists in psychiatry, psychology, neurology, pharmacology, molecular biology, genetics, physiology, neurochemistry, and related sciences.