Revolutionizing atopic dermatitis treatment: The efficacy of modified Qingxin decoction.

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Ying Guo, Jianzhou Ye, Guoying Miao
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引用次数: 0

Abstract

We aimed to explore the Modified Qingxin Decoction for Invigorating the Spleen (MQDIS) in the treatment of atopic dermatitis (AD) the efficacy and safety. We selected AD192 patients treated from June 2018 to June 2023 as a retrospective case-control study, and divided the patients into the observation group and the comparison group with 96 cases. Patients in the control group received conventional treatment. Observation group was treated with MQDIS on the basis of comparison group. Symptoms and signs, Scoring Atopic Dermatitis Index (SCORAD) score, itch score, dryness score and quality of life index were analyzed in the two groups. The improvement of skin area, severity, pruritus and sleep in the comparison group was better than that in the observation group, especially in the severity and sleep, and the statistical difference was very significant.(P-value<0.05).SCORAD score and itch degree of both groups decreased, the difference was statistically significant.(P-value<0.05).MQDIS for treating AD had a good effect on improving various points of skin lesion, dry points and quality of life, and the recurrence rate was lower, it was safe and effective.

革命性的特应性皮炎治疗:加味清心汤的疗效。
我们旨在探讨加味健脾清心汤(MQDIS)治疗特应性皮炎(AD)的疗效和安全性。我们选择2018年6月至2023年6月治疗的AD192例患者作为回顾性病例对照研究,将患者分为观察组和对照组各96例。对照组患者接受常规治疗。观察组患者在对照组治疗的基础上给予MQDIS治疗。分析两组患者的症状体征、评分特应性皮炎指数(scoad)评分、瘙痒评分、干燥评分及生活质量指数。对照组患者的皮肤面积、严重程度、瘙痒情况、睡眠改善情况均优于观察组,尤其是严重程度和睡眠改善情况,差异均有统计学意义。(P-value-value
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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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