An auxiliary role of deep neural network ophthalmic disease identification models in choosing medication treatment strategy.

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Wang Xi, Hongxu Sun, Huan Liu, Shouxi Lan, Xiaofei Dong
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引用次数: 0

Abstract

To evaluated a Deep Neural Network (DNN)-based ophthalmic disease diagnosis framework in facilitating personalized medication treatment plans using a prospective, single-center, randomized controlled clinical trial design. 500 patients were randomly assigned to either a DNN-aided experimental group or a control group receiving standard physician-based treatment plans. The primary outcomes were medication selection accuracy, clinical efficacy (assessed by BCVA and CMT), patient compliance, and adverse reaction management. Results showed that DNN-aided treatment plans significantly improved medication selection accuracy and treatment quality, with higher BCVA and CMT scores in the experimental group. Patients in the experimental group also demonstrated higher compliance and a trend towards lower adverse reaction rates. The study highlights the potential of DNN models to enhance ophthalmic disease management, offering precise and personalized treatment strategies with potential benefits for patient outcomes and safety as AI technology advances.

深度神经网络眼科疾病识别模型在药物治疗策略选择中的辅助作用。
采用前瞻性、单中心、随机对照临床试验设计,评估基于深度神经网络(DNN)的眼科疾病诊断框架在促进个性化药物治疗计划中的作用。500名患者被随机分配到dnn辅助的实验组和接受标准医生治疗计划的对照组。主要结局为药物选择准确性、临床疗效(BCVA和CMT评估)、患者依从性和不良反应管理。结果显示,dnn辅助治疗方案显著提高了药物选择准确性和治疗质量,实验组BCVA和CMT评分较高。实验组患者也表现出更高的依从性和更低的不良反应发生率的趋势。该研究强调了DNN模型在加强眼科疾病管理方面的潜力,随着人工智能技术的进步,提供精确和个性化的治疗策略,对患者的预后和安全性有潜在的好处。
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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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