Diagnosis and Treatment of Middle Ear Cholesterol Granuloma Involving the Middle Cranial fossa.

IF 1.9 3区医学 Q3 CLINICAL NEUROLOGY

Otology & Neurotology Pub Date : 2025-06-11 DOI:10.1097/MAO.0000000000004551

Shengqing Nian, Chenyu Chen, Yuqing Chen, Xihang Chen, Chang Lin

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引用次数: 0

Abstract

Objective: To evaluate the clinical features, surgical options, and prognosis of middle ear cholesterol granuloma involving the middle cranial fossa.

Study design: Retrospective cohort study.

Setting: Tertiary referral center.

Subjects and methods: Medical records of three patients with giant skull base cholesterol granuloma from 2006 to 2017 were retrospectively analyzed. The symptoms, signs, radiological features, treatment options, and prognosis were summarized.

Results: All patients underwent radical mastoidectomy and resection of skull base lesions by means of a retroauricular approach. Postoperative pathological diagnosis showed cholesterol granuloma. All patients were followed for more than 1 year. The symptoms were relieved, and there was no recurrence. Postoperative imaging showed that the skull base lesions were cleared and the compressed brain tissue recovered.

Conclusion: Patients with middle ear cholesterol granuloma involving the middle cranial fossa can be operated on by retroauricular approach. It can reduce the trauma of craniotomy and obtain good curative effect.

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累及中颅窝的中耳胆固醇肉芽肿的诊断与治疗。

目的：探讨累及中颅窝的中耳胆固醇肉芽肿的临床特点、手术选择及预后。研究设计：回顾性队列研究。单位：三级转诊中心。对象与方法：回顾性分析2006 ~ 2017年3例颅底巨大胆固醇肉芽肿患者的病历。总结其症状、体征、影像学特征、治疗方案及预后。结果：所有患者均经耳后入路行根治性乳突切除术和颅底病变切除术。术后病理诊断为胆固醇肉芽肿。所有患者随访1年以上。症状缓解，无复发。术后影像学显示颅底病变清除，脑组织受压恢复。结论：累及中颅窝的中耳胆固醇肉芽肿可经耳后入路手术治疗。可减少开颅外伤，取得良好的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Otology & Neurotology 医学-耳鼻喉科学

CiteScore

3.80

自引率

14.30%

发文量

509

审稿时长

3-6 weeks

期刊介绍： Otology & Neurotology publishes original articles relating to both clinical and basic science aspects of otology, neurotology, and cranial base surgery. As the foremost journal in its field, it has become the favored place for publishing the best of new science relating to the human ear and its diseases. The broadly international character of its contributing authors, editorial board, and readership provides the Journal its decidedly global perspective.