Age-stratified validation of the performance index (P-Index) as a metric for dual-task cost in functional mobility across the adult lifespan

IF 2.2 3区医学 Q3 NEUROSCIENCES

Gait & posture Pub Date : 2025-05-30 DOI:10.1016/j.gaitpost.2025.05.015

Aniuska Schiavo , Ana Paula Tiecker , Mariana dos Santos Oliveira , Nathalia Roman Ross , Fabiane de Oliveira Brauner , Gustavo Balbinot , Régis Gemerasca Mestriner

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引用次数: 0

Abstract

Objectives

To evaluate the predictive validity of the Performance Index (P-Index), a metric that integrates functional mobility and accuracy of cognitive responses to quantify dual-task (DT) performance, for cognitive outcomes measured by the Mini-Mental State Examination (MMSE) across the adult lifespan during the instrumented Timed Up and Go (iTUG) test.

Study design

This cross-sectional study included 247 participants from diverse age groups who completed single-task (ST) and dual-task (DT) iTUG tests in a semi-randomized order. The P-Index (range: 0–1) was calculated using iTUG completion times (measured with inertial sensors) and cognitive task accuracy (backward recitation of days of the week), with weighted components for time (W₁) and accuracy (W₂).

Main outcome measures

The relationship between the P-Index and MMSE scores.

Results

The optimal weighting for predictive accuracy was W₁ = 0.6 and W₂ = 0.4, yielding a P-Index threshold of 0.90 with a sensitivity of 0.69 and specificity of 0.64 for detecting MMSE scores ≥ 26. Participants who reported depressive symptoms (OR: 1.19, p = 0.02) were less likely to achieve MMSE ≥ 26. Conversely, each additional medication (OR: 1.04, p = 0005) and each unit increase in the P-Index significantly improved the odds of higher MMSE scores (OR: 3.89, p = 0.002).

Significance

The P-Index reliably measures dual-task interference and serves as a strong predictor of cognitive performance across the adult lifespan. It shows potential as a practical tool for cognitive-motor assessments and early detection of cognitive decline.

查看原文本刊更多论文

绩效指数（P-Index）作为成人生命周期中功能移动的双重任务成本度量的年龄分层验证

目的评估绩效指数（P-Index）的预测有效性，该指标整合了功能流动性和认知反应的准确性，以量化双任务（DT）的表现，在仪器计时的iTUG测试中，通过迷你精神状态检查（MMSE）测量了整个成人寿命期间的认知结果。本横断面研究包括247名来自不同年龄组的参与者，他们以半随机顺序完成单任务（ST）和双任务（DT） iTUG测试。p指数（范围：0-1）使用iTUG完成时间（用惯性传感器测量）和认知任务精度（向后背诵一周中的日子）计算，时间（W1）和精度（W2）加权。主要结果测量：p指数与MMSE评分之间的关系。结果MMSE评分≥ 26时，预测准确率的最佳权重分别为W1 = 0.6和W2 = 0.4，p指数阈值为0.90，灵敏度为0.69，特异性为0.64。报告抑郁症状的参与者（OR: 1.19, p = 0.02）达到MMSE≥ 26的可能性较小。相反，每增加一次用药（OR: 1.04, p = 0005）和p - index每增加一个单位均显著提高MMSE得分的几率（OR: 3.89, p = 0.002）。p -指数可靠地衡量双任务干扰，并作为一个强有力的预测在整个成人寿命的认知表现。它显示了作为认知运动评估和认知衰退早期检测的实用工具的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gait & posture 医学-神经科学

CiteScore

4.70

自引率

12.50%

发文量

616

审稿时长

6 months

期刊介绍： Gait & Posture is a vehicle for the publication of up-to-date basic and clinical research on all aspects of locomotion and balance. The topics covered include: Techniques for the measurement of gait and posture, and the standardization of results presentation; Studies of normal and pathological gait; Treatment of gait and postural abnormalities; Biomechanical and theoretical approaches to gait and posture; Mathematical models of joint and muscle mechanics; Neurological and musculoskeletal function in gait and posture; The evolution of upright posture and bipedal locomotion; Adaptations of carrying loads, walking on uneven surfaces, climbing stairs etc; spinal biomechanics only if they are directly related to gait and/or posture and are of general interest to our readers; The effect of aging and development on gait and posture; Psychological and cultural aspects of gait; Patient education.