A. Movasat Hajkhan, E. Rico Sánchez-Mateos, E. Fernández Fernández, E. Rabadán Rubio
{"title":"Protocolo diagnóstico de las aftas y las úlceras orales","authors":"A. Movasat Hajkhan, E. Rico Sánchez-Mateos, E. Fernández Fernández, E. Rabadán Rubio","doi":"10.1016/j.med.2025.06.008","DOIUrl":null,"url":null,"abstract":"<div><div>This protocol presents a comprehensive review of the differential diagnosis of aphthous ulcers and oral ulcers, frequent and recurrent conditions that may manifest as single or multiple lesions on the oral mucosa. The diagnostic process, which includes a systemic case history, physical examination, and the necessary complementary tests, is described. Aphthae are classified as simple or complex, describing their distinctive characteristics and progress. This work discusses the main etiologies, including recurrent aphthous stomatitis, viral and bacterial infections, neoplasms, systemic autoimmune diseases, gastrointestinal diseases, nutritional deficits, and pharmacological reactions. The importance of a differential diagnosis to identify the underlying cause is emphasized, especially in cases of complex aphthae that may be the initial manifestation of systemic diseases such as Behçet's disease or inflammatory bowel disease.</div></div>","PeriodicalId":100912,"journal":{"name":"Medicine - Programa de Formación Médica Continuada Acreditado","volume":"14 34","pages":"Pages 2099-2103"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine - Programa de Formación Médica Continuada Acreditado","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0304541225001465","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This protocol presents a comprehensive review of the differential diagnosis of aphthous ulcers and oral ulcers, frequent and recurrent conditions that may manifest as single or multiple lesions on the oral mucosa. The diagnostic process, which includes a systemic case history, physical examination, and the necessary complementary tests, is described. Aphthae are classified as simple or complex, describing their distinctive characteristics and progress. This work discusses the main etiologies, including recurrent aphthous stomatitis, viral and bacterial infections, neoplasms, systemic autoimmune diseases, gastrointestinal diseases, nutritional deficits, and pharmacological reactions. The importance of a differential diagnosis to identify the underlying cause is emphasized, especially in cases of complex aphthae that may be the initial manifestation of systemic diseases such as Behçet's disease or inflammatory bowel disease.