Muthu Thiruvengadam , Hee-Youn Chi , Hee-Jin Choi , Bum-Su Jung , Seung-Bin Lee , Yunwoo Park , Dagyeom Jeon , Fatih Ciftci , Mohammad Ali Shariati , Seung-Hyun Kim
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引用次数: 0
Abstract
The demand for highly sensitive and specific biosensors is growing rapidly across multiple sectors, including medical diagnostics, environmental monitoring, pathogen detection, and food safety. This review critically explores the advancements in nano-enabled biosensor technologies, focusing on bio-based nanosensors synthesized using plant-derived phytochemicals, cellulose, and lignin. These naturally derived materials serve as eco-friendly stabilizing and reducing agents for the formation of functional nanoparticles (NPs). This review (i) discusses the synthesis and characterization techniques of bio-nanosensors; (ii) examines their physical, chemical, and biological interactions; and (iii) evaluates their applications in early disease screening, diagnostics (e.g., cancer and diabetes), and the detection of pathogens, pollutants, and toxins. In addition, we address key challenges associated with bio-based nanomaterials, including NP toxicity, biocompatibility, and the need for appropriate regulatory frameworks. Furthermore, we highlight the growing role of artificial intelligence, machine learning, and the Internet of Things in enhancing biosensor performance and commercialization. This review concludes by emphasizing the potential of bio-based nanosensors for clinical, environmental, and food safety applications, while advocating the development of micro- and disposable sensor formats. By highlighting the potential and limitations of bionanosensors, this review provides a foundation for future research and the development of clinical and commercial applications.
期刊介绍:
Industrial Crops and Products is an International Journal publishing academic and industrial research on industrial (defined as non-food/non-feed) crops and products. Papers concern both crop-oriented and bio-based materials from crops-oriented research, and should be of interest to an international audience, hypothesis driven, and where comparisons are made statistics performed.