{"title":"The use of technical grade chemicals and on-site production of ammonium nitrate: a cost-effective and safer approach to Thiel embalming.","authors":"Napawan Taradolpisut, Wattana Weerachatyanukul, Worawit Suphamungmee, Somluk Asuvapongpatana, Torsak Luanphaisarnnont, Arada Chaiyamoon, Thewarid Berkban, Tyler Halliwell, Tracey Wilkinson, Athikhun Suwannakhan","doi":"10.1007/s00276-025-03672-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>While Thiel embalming effectively preserves cadavers in a lifelike and flexible state, its implementation is constrained by high costs and the use of ammonium nitrate, which may be restricted in certain countries due to regulatory controls and safety concerns. This study aims to develop a more economical and safer approach to Thiel embalming by using technical grade chemicals and synthesizing ammonium nitrate on-site and, both overcoming economic barriers to Thiel embalming and addressing regulatory constraints associated with ammonium nitrate.</p><p><strong>Methods: </strong>In the present study, technical grades were used instead of reagent grades. Ammonium nitrate was synthesized through a controlled reaction of nitric acid and ammonium hydroxide under strict safety protocols. The solution was incorporated into Thiel embalming fluids and used for arterial and venous embalming of 28 cadavers at two institutions.</p><p><strong>Results: </strong>The cadavers embalmed using the methods presented in this study were comparable to conventional Thiel-embalmed cadavers, preserving tissue flexibility, color, and structural integrity. The only notable difference was the reduced submersion duration, which was limited to three to four months.and the technique effectively mitigated the hazards of ammonium nitrate storage.</p><p><strong>Conclusion: </strong>The use of technical grade chemicals, combined with on-site production of ammonium nitrate, presents a more cost-effective alternative for Thiel embalming, particularly in regions with stringent regulations, making Thiel embalming more accessible for anatomy departments worldwide.</p>","PeriodicalId":49461,"journal":{"name":"Surgical and Radiologic Anatomy","volume":"47 1","pages":"157"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical and Radiologic Anatomy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00276-025-03672-2","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: While Thiel embalming effectively preserves cadavers in a lifelike and flexible state, its implementation is constrained by high costs and the use of ammonium nitrate, which may be restricted in certain countries due to regulatory controls and safety concerns. This study aims to develop a more economical and safer approach to Thiel embalming by using technical grade chemicals and synthesizing ammonium nitrate on-site and, both overcoming economic barriers to Thiel embalming and addressing regulatory constraints associated with ammonium nitrate.
Methods: In the present study, technical grades were used instead of reagent grades. Ammonium nitrate was synthesized through a controlled reaction of nitric acid and ammonium hydroxide under strict safety protocols. The solution was incorporated into Thiel embalming fluids and used for arterial and venous embalming of 28 cadavers at two institutions.
Results: The cadavers embalmed using the methods presented in this study were comparable to conventional Thiel-embalmed cadavers, preserving tissue flexibility, color, and structural integrity. The only notable difference was the reduced submersion duration, which was limited to three to four months.and the technique effectively mitigated the hazards of ammonium nitrate storage.
Conclusion: The use of technical grade chemicals, combined with on-site production of ammonium nitrate, presents a more cost-effective alternative for Thiel embalming, particularly in regions with stringent regulations, making Thiel embalming more accessible for anatomy departments worldwide.
期刊介绍:
Anatomy is a morphological science which cannot fail to interest the clinician. The practical application of anatomical research to clinical problems necessitates special adaptation and selectivity in choosing from numerous international works. Although there is a tendency to believe that meaningful advances in anatomy are unlikely, constant revision is necessary. Surgical and Radiologic Anatomy, the first international journal of Clinical anatomy has been created in this spirit.
Its goal is to serve clinicians, regardless of speciality-physicians, surgeons, radiologists or other specialists-as an indispensable aid with which they can improve their knowledge of anatomy. Each issue includes: Original papers, review articles, articles on the anatomical bases of medical, surgical and radiological techniques, articles of normal radiologic anatomy, brief reviews of anatomical publications of clinical interest.
Particular attention is given to high quality illustrations, which are indispensable for a better understanding of anatomical problems.
Surgical and Radiologic Anatomy is a journal written by anatomists for clinicians with a special interest in anatomy.