Investigation of factors influencing anxiety and depression symptoms after therapy in 200 patients diagnosed with primary liver cancer.

IF 3.4 4区医学 Q1 PSYCHIATRY

World Journal of Psychiatry Pub Date : 2025-05-19 DOI:10.5498/wjp.v15.i5.101450

Gang Cheng, Xin-Sheng Li, Meng Zhang, Yan-Min Wu

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引用次数: 0

Abstract

Background: Patients undergoing interventional therapy for liver cancer experience severe psychological pain and are prone to anxiety and depression.

Aim: To explore factors influencing anxiety and depression symptoms in 200 patients diagnosed with primary liver cancer.

Methods: Data from 200 individuals diagnosed with primary liver cancer and admitted to the authors' hospital (January 2022 to January 2024) were divided into 2 groups according to psychological status: Normal (n = 100); and anxiety and depression (n = 100). Through a questionnaire survey of patients and their families, single and multifactor factors of anxiety and depression in the postoperative interventional treatment of patients with primary liver cancer were analyzed.

Results: Univariate analysis revealed no statistical differences between the 2 groups in terms of chronic disease, sex, liver function, Child grade, and age (P > 0.05). However, there were statistical differences in payment method, disease cognition, number of interventional treatments, per capita income, and educational level (P < 0.05). Multivariate logistic regression analysis revealed that educational level, per capita income, disease cognition, payment method, and number of interventional treatments were all independent factors influencing postoperative anxiety and depression symptoms after interventional therapy in patients diagnosed with primary liver cancer, and the comparisons were statistically significant (P < 0.05).

Conclusion: Analysis of associated risk factors can strengthen the clinical screening of patients with liver cancer at high risk for postoperative anxiety and depression symptoms and improve their prognosis.

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200例原发性肝癌患者治疗后焦虑、抑郁症状的影响因素调查

背景：肝癌介入治疗患者心理疼痛严重，易出现焦虑和抑郁。目的：探讨200例原发性肝癌患者焦虑、抑郁症状的影响因素。方法：选取2022年1月~ 2024年1月在笔者所在医院就诊的200例原发性肝癌患者，根据患者的心理状态分为两组：正常组（n = 100）；焦虑和抑郁（n = 100）。通过对患者及其家属的问卷调查，分析原发性肝癌患者术后介入治疗中焦虑、抑郁的单因素和多因素影响因素。结果：单因素分析显示，两组患者在慢性疾病、性别、肝功能、儿童分级、年龄等方面无统计学差异（P < 0.05）。但在支付方式、疾病认知、介入治疗次数、人均收入、文化程度等方面差异有统计学意义（P < 0.05）。多因素logistic回归分析显示，文化程度、人均收入、疾病认知、支付方式、介入治疗次数均是影响原发性肝癌患者介入治疗后焦虑、抑郁症状的独立因素，差异均有统计学意义（P < 0.05）。结论：分析相关危险因素可加强对肝癌术后焦虑抑郁症状高危患者的临床筛查，改善其预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Psychiatry PSYCHIATRY-

自引率

6.50%

发文量

110

期刊介绍： The World Journal of Psychiatry (WJP) is a high-quality, peer reviewed, open-access journal. The primary task of WJP is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of psychiatry. In order to promote productive academic communication, the peer review process for the WJP is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJP are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in psychiatry.