Control of aflatoxin in broiler feeds through dietary supplementation with Pichia kudriavzevii B-5P: effects on performance, serum biochemistry and histopathological change - a promosing strategy.
IF 4.2 3区 生物学Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
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引用次数: 0
Abstract
Aflatoxin is a mycotoxin that contaminates many grain feed ingredients, especially corn. Pichia kudriavzevii B-5P is a yeast strain with potential application in the mitigation of Aspergillus flavus and its associated aflatoxins. This research aims to optimize the dose of Pichia kudriavzevii B-5P as a toxin binder in corn containing aflatoxin in broiler chicken rations along with in vivo evaluation of its protection efficiency on performance, carcass characteristics, serum biochemistry and histopatholical alteration in the liver, kidneys and intestines. This research used a Completely Randomized Design (CRD), 4 treatments and 5 replications. Treatment consisted of T1: control (no aflatoxin); T2: 0,1% P. kudriavzevii B-5P; T3: 0,2% P. kudriavzevii B-5P; T4: 0,3% P. kudriavzevii B-5P. Performance (consumption, weight gain, feed conversion, live weight, and carcass), abdominal fat, percentage of organ weight (liver, kidney, and small intestine), and total protein, albumin, and globulin were not significantly different (p > 0.05) between the control group (without aflatoxin) and the group of chickens fed aflatoxin (191.95 ppb) + Pichia kudriavzevii B-5P. Histopathologically, the liver, kidneys, and small intestine showed mild damage that tended to improve with the administration of P. kudriavzevii B-5P, thereby not affecting organ function. The results of the study concluded that giving Pichia kudriavzevii B-5P as much as 0.1% in feed can overcome aflatoxin contamination with a level of 191.95 ppb in broiler chickens.
期刊介绍:
World Journal of Microbiology and Biotechnology publishes research papers and review articles on all aspects of Microbiology and Microbial Biotechnology.
Since its foundation, the Journal has provided a forum for research work directed toward finding microbiological and biotechnological solutions to global problems. As many of these problems, including crop productivity, public health and waste management, have major impacts in the developing world, the Journal especially reports on advances for and from developing regions.
Some topics are not within the scope of the Journal. Please do not submit your manuscript if it falls into one of the following categories:
· Virology
· Simple isolation of microbes from local sources
· Simple descriptions of an environment or reports on a procedure
· Veterinary, agricultural and clinical topics in which the main focus is not on a microorganism
· Data reporting on host response to microbes
· Optimization of a procedure
· Description of the biological effects of not fully identified compounds or undefined extracts of natural origin
· Data on not fully purified enzymes or procedures in which they are applied
All articles published in the Journal are independently refereed.