Theory of Mind and Neurocognition in Bipolar Mania Patients and Their Unaffected First-Degree Relatives.

IF 2.5 3区心理学 Q2 PSYCHOLOGY, CLINICAL

Journal of Clinical Psychology Pub Date : 2025-06-10 DOI:10.1002/jclp.70003

Jing Zeng, Tie-Bang Liu, Yang-Hui Liu

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引用次数: 0

Abstract

Background: Cognitive impairment in manic patients involves neurocognitive and theory of mind (ToM) impairments. This study aims to investigate cognitive impairment among manic patients and their first-degree relatives (FDRs).

Methods: A total of 31 manic inpatients, 31 unaffected relatives, and 30 healthy controls (HCs) were investigated using the Reading the Mind in Eye Test (RMET) and Hinting Task (HT). The intelligence quotient (IQ), attention, working memory, executive functions, fluency and processing speed were also assessed.

Results: Patients and their relatives scored lower than controls on Theory of Mind reasoning and several neurocognitive measures. Regression analysis of the total sample indicated that a mania diagnosis or a FDR was strongly related to lower ToM reasoning performance. The deficits in ToM among patients were related to years of education.

Conclusions: Due to the comparable performance of ToM between patients and their relatives, the reasoning aspect of ToM may represent a trait marker for bipolar disorder (BD). The deficits in ToM in patients with BD are partly independent of neurocognition.

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双相躁狂症患者及其未受影响的一级亲属的心理理论和神经认知。

背景：躁狂患者的认知障碍包括神经认知和心理理论（ToM）障碍。本研究旨在探讨躁狂患者及其一级亲属的认知功能障碍。方法：采用眼读心术测验（RMET）和暗示任务（HT）对31例躁狂住院患者、31例未患亲属和30例健康对照进行调查。智商（IQ）、注意力、工作记忆、执行功能、流畅性和处理速度也被评估。结果：患者及其亲属在心理理论推理和若干神经认知测试中的得分低于对照组。总样本的回归分析表明，躁狂诊断或FDR与较低的ToM推理表现密切相关。患者的ToM缺陷与受教育年限有关。结论：由于患者及其亲属之间的ToM表现具有可比性，因此ToM的推理方面可能代表双相情感障碍（BD）的特征标记。双相障碍患者的ToM缺陷部分独立于神经认知。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Psychology PSYCHOLOGY, CLINICAL-

CiteScore

5.40

自引率

3.30%

发文量

177

期刊介绍： Founded in 1945, the Journal of Clinical Psychology is a peer-reviewed forum devoted to research, assessment, and practice. Published eight times a year, the Journal includes research studies; articles on contemporary professional issues, single case research; brief reports (including dissertations in brief); notes from the field; and news and notes. In addition to papers on psychopathology, psychodiagnostics, and the psychotherapeutic process, the journal welcomes articles focusing on psychotherapy effectiveness research, psychological assessment and treatment matching, clinical outcomes, clinical health psychology, and behavioral medicine.