Application of 3D printed calcium phosphate cement scaffolds in open wedge high tibial osteotomy (owHTO) – A retrospective clinical evaluation

IF 3 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materialia Pub Date : 2025-06-07 DOI:10.1016/j.mtla.2025.102459

Richard Frank Richter , Frank Pries , Volker Alt , Anja Lode , Sascha Heinemann

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引用次数: 0

Abstract

Calcium phosphate cements (CPC) are widely used materials for filling bone defects and bone augmentation. Developments in CPC formulations have led to a practically unlimited processability, allowing to use these formulations for new fabrication methods like extrusion-based 3D-printing. This study shows the application of INNOTERE 3D scaffolds, printed from a CPC paste and allowed to set, for open wedge high tibial osteotomy. It is the first time that a 3D-printed, certified medical device in this product class is used in a routine clinical application. The objective of this retrospective clinical evaluation is to assess the safety and clinical performance in regards to bone healing, osteointegration and resorption. In comparison to the also commercially available OSferion, a conventional, sintered ceramic, the 3D-printed scaffolds show no inferiority. This marks the first time that such a 3D-printed medical product is used in a broad evaluation regarding its clinical outcome.

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3D打印磷酸钙水泥支架在开楔高位胫骨截骨术中的应用——回顾性临床评价

磷酸钙骨水泥（CPC）是一种广泛应用于骨缺损填充和骨增强的材料。CPC配方的发展导致了几乎无限的可加工性，允许将这些配方用于新的制造方法，如基于挤压的3d打印。本研究展示了INNOTERE 3D支架的应用，该支架由CPC粘贴打印并允许设置，用于开楔高位胫骨截骨。这是该产品类别中经过认证的3d打印医疗设备首次用于常规临床应用。本回顾性临床评价的目的是评估在骨愈合、骨整合和骨吸收方面的安全性和临床表现。与市面上同样可以买到的OSferion（一种传统的烧结陶瓷）相比，3d打印支架没有任何劣势。这标志着这种3d打印医疗产品首次被广泛用于临床结果评估。

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来源期刊

Materialia MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

6.40

自引率

2.90%

发文量

345

审稿时长

36 days

期刊介绍： Materialia is a multidisciplinary journal of materials science and engineering that publishes original peer-reviewed research articles. Articles in Materialia advance the understanding of the relationship between processing, structure, property, and function of materials. Materialia publishes full-length research articles, review articles, and letters (short communications). In addition to receiving direct submissions, Materialia also accepts transfers from Acta Materialia, Inc. partner journals. Materialia offers authors the choice to publish on an open access model (with author fee), or on a subscription model (with no author fee).