Origins and functions of microbiome rhythms

IF 20.6 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2025-06-11 DOI:10.1016/j.chom.2025.05.017

Silke Kiessling, Shuaitong Liu, Dirk Haller, Christoph A. Thaiss

引用次数: 0

Abstract

Daily oscillations in microbiota composition and function are emerging as an important element in host-microbiota interactions. Here, we summarize features of the microbiota that undergo diurnal rhythms, their development, their impact on the biology of the host, and their relevance to human health and disease. In particular, we focus on the intrinsic and extrinsic factors that regulate microbiota oscillations and the multifaceted roles that microbiota rhythmicity plays in host physiology, immunity, and metabolism. Given the pervasive impact of intestinal microorganisms on host health, understanding the origins and functions of microbiota rhythms is a critical aspect of the circadian biology of the meta-organism.

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微生物组节律的起源和功能

微生物群组成和功能的日常振荡正在成为宿主-微生物群相互作用的重要因素。在这里，我们总结了经历昼夜节律的微生物群的特征，它们的发育，它们对宿主生物学的影响，以及它们与人类健康和疾病的相关性。特别是，我们关注调节微生物群振荡的内在和外在因素，以及微生物群节律性在宿主生理、免疫和代谢中发挥的多方面作用。鉴于肠道微生物对宿主健康的普遍影响，了解微生物群节律的起源和功能是元生物昼夜节律生物学的一个关键方面。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.